Nasal mucoepidermoid carcinoma after radiotherapy: Case report
Introduction Mucoepidermoid carcinoma (MEC) is a tumor originated from the epithelium of the glandular excretory ducts and has highly variable biological potential. It is the most prevalent cancer of the salivary glands. The present report aims to describe a case of nasal mucoepidermoid carcinoma th...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações Ltda.
2022-01-01
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| Series: | Brazilian Neurosurgery |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1739269 |
| _version_ | 1819280430599241728 |
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| author | Breno Nery Victor Ribeiro Xavier Costa Glaudir Donato Pinto Júnior Andrey Maia Silva Diniz Lucas Ribeiro de Moraes Freitas Davi Coutinho Marcelino Guerra Leone José Alencar de Sousa Segundo Mariana Junqueira Reis Enout Eduardo Quaggio Renan Lopez Rivero |
| author_facet | Breno Nery Victor Ribeiro Xavier Costa Glaudir Donato Pinto Júnior Andrey Maia Silva Diniz Lucas Ribeiro de Moraes Freitas Davi Coutinho Marcelino Guerra Leone José Alencar de Sousa Segundo Mariana Junqueira Reis Enout Eduardo Quaggio Renan Lopez Rivero |
| author_sort | Breno Nery |
| collection | DOAJ |
| description | Introduction Mucoepidermoid carcinoma (MEC) is a tumor originated from the epithelium of the glandular excretory ducts and has highly variable biological potential. It is the most prevalent cancer of the salivary glands. The present report aims to describe a case of nasal mucoepidermoid carcinoma that developed after adjuvant radiotherapy (RT) treatment of a recurrent pituitary macroadenoma.
Case Report Male patient, 62 years old, presented with recurrent nasal epistaxis on the right, associated with intense pulsatile headache, visual analogical scale (VAS) 10/10, with improvement only with the use of opioids and morphine. After undergoing oncological screening and study by imaging exams, the presence of an expansive seal lesion with suprasellar extension was seen, involving the medial wall of the cavernous segment of the right carotid artery and the anterior cerebral artery, as well as the presence of a new expansive lesion in the right nasal cavity, with ethmoid bone invasion superiorly and medial orbit wall invasion laterally, compressing the ipsilateral optic nerve canal.
Discussion Sinonasal neoplasms represent a small portion of all malignancies of the upper aerodigestive tract, accounting for < 5% of these neoplasms. The development of MEC involves risk factors such as occupational issues, history of trauma and surgery involving the nasal area, and radiation exposure, as in previous RT.
Conclusion Mucoepidermoid carcinoma is an uncommon neoplasia and can be associated with RT treatment, as used in cases of recurrent pituitary macroadenoma. In general, surgical resection to obtain free margins of neoplastic tissue is the aimed treatment, seeking better prognosis. |
| first_indexed | 2024-12-24T00:43:40Z |
| format | Article |
| id | doaj.art-cc1a669c368b495894066369b0260cc5 |
| institution | Directory Open Access Journal |
| issn | 0103-5355 2359-5922 |
| language | English |
| last_indexed | 2024-12-24T00:43:40Z |
| publishDate | 2022-01-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | Brazilian Neurosurgery |
| spelling | doaj.art-cc1a669c368b495894066369b0260cc52022-12-21T17:23:53ZengThieme Revinter Publicações Ltda.Brazilian Neurosurgery0103-53552359-59222022-01-014101e85e8910.1055/s-0041-1739269Nasal mucoepidermoid carcinoma after radiotherapy: Case reportBreno Nery0Victor Ribeiro Xavier Costa1Glaudir Donato Pinto Júnior2Andrey Maia Silva Diniz3Lucas Ribeiro de Moraes Freitas4Davi Coutinho Marcelino Guerra Leone5José Alencar de Sousa Segundo6Mariana Junqueira Reis Enout7Eduardo Quaggio8Renan Lopez Rivero9Department of Neurosurgery, São Francisco Hospital, Ribeirão Preto, SP, BrazilFaculdade de Ciências Médicas da Paraíba, João Pessoa, PB, BrazilCentro de Ciências Médicas, Universidade Federal da Paraíba, João Pessoa, PB, BrazilCentro de Ciências Médicas, Universidade Federal da Paraíba, João Pessoa, PB, BrazilCentro de Ciências Médicas, Universidade Federal da Paraíba, João Pessoa, PB, BrazilCentro de Ciências Médicas, Universidade Federal da Paraíba, João Pessoa, PB, BrazilDepartment of Neurosurgery, Hospital Beneficência Portuguesa, Ribeirão Preto, SP, BrazilDepartment of Otolaryngology, Universidade Federal de São Paulo, São Paulo, SP, BrazilDepartment of Neurosurgery, São Francisco Hospital, Ribeirão Preto, SP, BrazilSchool of Medical Sciences, University of Bristol, Bristol, United KingdomIntroduction Mucoepidermoid carcinoma (MEC) is a tumor originated from the epithelium of the glandular excretory ducts and has highly variable biological potential. It is the most prevalent cancer of the salivary glands. The present report aims to describe a case of nasal mucoepidermoid carcinoma that developed after adjuvant radiotherapy (RT) treatment of a recurrent pituitary macroadenoma. Case Report Male patient, 62 years old, presented with recurrent nasal epistaxis on the right, associated with intense pulsatile headache, visual analogical scale (VAS) 10/10, with improvement only with the use of opioids and morphine. After undergoing oncological screening and study by imaging exams, the presence of an expansive seal lesion with suprasellar extension was seen, involving the medial wall of the cavernous segment of the right carotid artery and the anterior cerebral artery, as well as the presence of a new expansive lesion in the right nasal cavity, with ethmoid bone invasion superiorly and medial orbit wall invasion laterally, compressing the ipsilateral optic nerve canal. Discussion Sinonasal neoplasms represent a small portion of all malignancies of the upper aerodigestive tract, accounting for < 5% of these neoplasms. The development of MEC involves risk factors such as occupational issues, history of trauma and surgery involving the nasal area, and radiation exposure, as in previous RT. Conclusion Mucoepidermoid carcinoma is an uncommon neoplasia and can be associated with RT treatment, as used in cases of recurrent pituitary macroadenoma. In general, surgical resection to obtain free margins of neoplastic tissue is the aimed treatment, seeking better prognosis.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1739269mucoepidermoid carcinomaneurosurgeryradiotherapypituitary adenoma |
| spellingShingle | Breno Nery Victor Ribeiro Xavier Costa Glaudir Donato Pinto Júnior Andrey Maia Silva Diniz Lucas Ribeiro de Moraes Freitas Davi Coutinho Marcelino Guerra Leone José Alencar de Sousa Segundo Mariana Junqueira Reis Enout Eduardo Quaggio Renan Lopez Rivero Nasal mucoepidermoid carcinoma after radiotherapy: Case report Brazilian Neurosurgery mucoepidermoid carcinoma neurosurgery radiotherapy pituitary adenoma |
| title | Nasal mucoepidermoid carcinoma after radiotherapy: Case report |
| title_full | Nasal mucoepidermoid carcinoma after radiotherapy: Case report |
| title_fullStr | Nasal mucoepidermoid carcinoma after radiotherapy: Case report |
| title_full_unstemmed | Nasal mucoepidermoid carcinoma after radiotherapy: Case report |
| title_short | Nasal mucoepidermoid carcinoma after radiotherapy: Case report |
| title_sort | nasal mucoepidermoid carcinoma after radiotherapy case report |
| topic | mucoepidermoid carcinoma neurosurgery radiotherapy pituitary adenoma |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1739269 |
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