Rescuing the Inhibitory Effect of the Salivary Gland Hypertrophy Virus of <i>Musca domestica</i> on Mating Behavior

Infection with salivary gland hypertrophy virus (<i>Md</i>SGHV) of <i>Musca domestica</i> prevents female flies from accepting copulation attempts by healthy or virus-infected males. This study focused on supplemental hormonal rescue therapy for mating behavior in virus-infec...

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Bibliographic Details
Main Authors: Marissa Gallagher, Arianna Ramirez, Christopher J. Geden, John G. Stoffolano
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Insects
Subjects:
Online Access:https://www.mdpi.com/2075-4450/14/5/416
Description
Summary:Infection with salivary gland hypertrophy virus (<i>Md</i>SGHV) of <i>Musca domestica</i> prevents female flies from accepting copulation attempts by healthy or virus-infected males. This study focused on supplemental hormonal rescue therapy for mating behavior in virus-infected female house flies. The inhibitory effect of the virus on mating behavior in females injected with <i>Md</i>SGHV was reversed by hormonal therapy in the form of octopamine injections, topical application of methoprene, or both therapies combined along with 20-hydroxyecdysone. Infected females whose mating responsiveness had been restored continued to have other viral pathologies associated with infection such as hypertrophy of the salivary glands and a lack of ovarian development.
ISSN:2075-4450