Relationship between Bipolar Disorder and Rheumatoid Arthritis

Rheumatoid arthritis is a chronic autoimmune disease that is characterized by synovitis, systemic inflammation, arthritis and vasculitis, anemia, mononeuritis, pulmonary fibrosis, and can cause joint destruction, limitation of joint movements and impairment of the patient's quality of life if n...

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Main Authors: Melike Mandacı, Aslı Sarandöl, Cengiz Akkaya
Format: Article
Language:English
Published: Psikiyatride Güncel Yaklaşımlar 2022-06-01
Series:Psikiyatride Güncel Yaklaşımlar
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/1718414
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author Melike Mandacı
Aslı Sarandöl
Cengiz Akkaya
author_facet Melike Mandacı
Aslı Sarandöl
Cengiz Akkaya
author_sort Melike Mandacı
collection DOAJ
description Rheumatoid arthritis is a chronic autoimmune disease that is characterized by synovitis, systemic inflammation, arthritis and vasculitis, anemia, mononeuritis, pulmonary fibrosis, and can cause joint destruction, limitation of joint movements and impairment of the patient's quality of life if not treated in right time and adequate manner. In addition to joint symptoms, neuropsychiatric symptoms such as cognitive dysfunction, behavioral changes, and mood changes may accompany rheumatoid arthritis patients. It is thought that neuroinflammatory process in rheumatoid arthritis patients, increase in proinflammatory cytokine levels in plasma; side effects of drugs used for a long time, disability that occurs with the disease, and possible common gene regions may cause these symptoms. An increasing number of studies are being published on psychiatric symptoms and disorders in patients with rheumatoid arthritis. There are many studies focusing especially on its relationship with anxiety disorders and major depressive disorder. There are increasing numbers of studies showing that the impairment of immune functions is involved in the etiology of bipolar disorder. The changes in cytokine levels in the plasma of bipolar disorder patients supports this argument. The relationship between various autoimmune diseases and bipolar disorder continues to be examined. In people with rheumatological diseases, it is important to be careful in psychiatric comorbidities in terms of patient compliance and clinical course.
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spelling doaj.art-cc1be2a6d7d140ee98ad67577843d5d02024-02-03T06:26:43ZengPsikiyatride Güncel YaklaşımlarPsikiyatride Güncel Yaklaşımlar1309-06581309-06742022-06-0114213114210.18863/pgy.921569496Relationship between Bipolar Disorder and Rheumatoid ArthritisMelike MandacıAslı SarandölCengiz AkkayaRheumatoid arthritis is a chronic autoimmune disease that is characterized by synovitis, systemic inflammation, arthritis and vasculitis, anemia, mononeuritis, pulmonary fibrosis, and can cause joint destruction, limitation of joint movements and impairment of the patient's quality of life if not treated in right time and adequate manner. In addition to joint symptoms, neuropsychiatric symptoms such as cognitive dysfunction, behavioral changes, and mood changes may accompany rheumatoid arthritis patients. It is thought that neuroinflammatory process in rheumatoid arthritis patients, increase in proinflammatory cytokine levels in plasma; side effects of drugs used for a long time, disability that occurs with the disease, and possible common gene regions may cause these symptoms. An increasing number of studies are being published on psychiatric symptoms and disorders in patients with rheumatoid arthritis. There are many studies focusing especially on its relationship with anxiety disorders and major depressive disorder. There are increasing numbers of studies showing that the impairment of immune functions is involved in the etiology of bipolar disorder. The changes in cytokine levels in the plasma of bipolar disorder patients supports this argument. The relationship between various autoimmune diseases and bipolar disorder continues to be examined. In people with rheumatological diseases, it is important to be careful in psychiatric comorbidities in terms of patient compliance and clinical course.https://dergipark.org.tr/tr/download/article-file/1718414rheumatoid arthritisinflammationpsychoneuroimmunologybipolar disorder
spellingShingle Melike Mandacı
Aslı Sarandöl
Cengiz Akkaya
Relationship between Bipolar Disorder and Rheumatoid Arthritis
Psikiyatride Güncel Yaklaşımlar
rheumatoid arthritis
inflammation
psychoneuroimmunology
bipolar disorder
title Relationship between Bipolar Disorder and Rheumatoid Arthritis
title_full Relationship between Bipolar Disorder and Rheumatoid Arthritis
title_fullStr Relationship between Bipolar Disorder and Rheumatoid Arthritis
title_full_unstemmed Relationship between Bipolar Disorder and Rheumatoid Arthritis
title_short Relationship between Bipolar Disorder and Rheumatoid Arthritis
title_sort relationship between bipolar disorder and rheumatoid arthritis
topic rheumatoid arthritis
inflammation
psychoneuroimmunology
bipolar disorder
url https://dergipark.org.tr/tr/download/article-file/1718414
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AT aslısarandol relationshipbetweenbipolardisorderandrheumatoidarthritis
AT cengizakkaya relationshipbetweenbipolardisorderandrheumatoidarthritis