The eff ect of poliodoxin and tilmox 25% on the morphological and biochemical parameters of the blood of broiler chickens

The article presents the results of studies of the eff ect of the drug “Poledoxin”, which belongs to the group of tetracyclines and the drug “Tilmox 25%”, belonging to the group of macrolides, on some morphological and biochemical parameters of blood of Coobb-500 broiler chickens. It has been establi...

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Main Authors: Tyshkivskaya A., V. Dukhnitsky, Tyshkivsky M.
Format: Article
Language:English
Published: Bila Tserkva National Agrarian University 2020-05-01
Series:Науковий вісник ветеринарної медицини
Subjects:
Online Access:http://nvvm.btsau.edu.ua/sites/all/modules/pubdlcnt/pubdlcnt.php?fid=1010
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author Tyshkivskaya A.
V. Dukhnitsky
Tyshkivsky M.
author_facet Tyshkivskaya A.
V. Dukhnitsky
Tyshkivsky M.
author_sort Tyshkivskaya A.
collection DOAJ
description The article presents the results of studies of the eff ect of the drug “Poledoxin”, which belongs to the group of tetracyclines and the drug “Tilmox 25%”, belonging to the group of macrolides, on some morphological and biochemical parameters of blood of Coobb-500 broiler chickens. It has been established that the use of the preparations “Poledoxin” and “Tilmox 25 %” for healthy broiler chickens according to the scheme recommended for treating birds with ornithobacteriosis and infections complicated by the causative agent of ornithobacteriosis does not cause changes in the clinical condition and behavioral reactions of the bird. A blood test found that under the infl uence of the drug “Poledoxin”, the number of red blood cells in the blood of broiler chickens increased by 4–59 % (p< 0,01) in chickens which used the drug “Tilmox 25 %” – by 5–46 % relative to control. The hematocrit value was less than the control indicator by 8 % in chickens that were treated with Poledoxin after 6 days of experiment (p< 0,05) in chickens that were used with tilmox 25 % – by 10 % (p< 0,05) through 6 and 9 days of experience. The hemoglobin content in the blood of poultry of the studied groups one day after drinking antibiotic solutions was less than the control by 7 and 8 %, respectively (p< 0,05, p< 0,01), and after 4 days – by 11 and 10 % (p< 0,01). Under the infl uence of Pledoxin, the volume of 1 erythrocyte (MCV, μm 3) in the blood of chickens was less than the control by 23–39 % (p< 0,05, p< 0,01), and when exposed to tilmox 25% – by 16–35 % (p< 0,01). The hemoglobin content in 1 erythrocyte (MCH, pg) was 62–83 % of the control index when exposed to Poledoxin (p< 0,01) and 69–86 % when exposed to tylmox 25 % (p< 0,01). The number of leukocytes in the blood of a bird under the infl uence of “Poledoxin” decreased by 8 % after a day (p< 0,01), and increased by 6 and 7 % after 3 and 4 days (p< 0,01). A decrease in the number of leukocytes in the blood of chickens of both research groups by 5–11 % (p< 0,001, p< 0,01) was established after 8 and 9 days.
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spelling doaj.art-cc1e4f82b6f64106a56ee86160bd025d2022-12-22T02:48:04ZengBila Tserkva National Agrarian UniversityНауковий вісник ветеринарної медицини2310-49022415-75892020-05-011727910.33245/2310-4902-2020-154-1-72-79The eff ect of poliodoxin and tilmox 25% on the morphological and biochemical parameters of the blood of broiler chickensTyshkivskaya A.0https://orcid.org/0000-0003-4419-2174V. Dukhnitsky1https://orcid.org/0000-0002-9670-1244Tyshkivsky M.2https://orcid.org/0000-0003-0826-5276National University of Life and Environmental Sciences of UkraineNational University of Life and Environmental Sciences of UkraineBila Tserkva National Agrarian UniversityThe article presents the results of studies of the eff ect of the drug “Poledoxin”, which belongs to the group of tetracyclines and the drug “Tilmox 25%”, belonging to the group of macrolides, on some morphological and biochemical parameters of blood of Coobb-500 broiler chickens. It has been established that the use of the preparations “Poledoxin” and “Tilmox 25 %” for healthy broiler chickens according to the scheme recommended for treating birds with ornithobacteriosis and infections complicated by the causative agent of ornithobacteriosis does not cause changes in the clinical condition and behavioral reactions of the bird. A blood test found that under the infl uence of the drug “Poledoxin”, the number of red blood cells in the blood of broiler chickens increased by 4–59 % (p< 0,01) in chickens which used the drug “Tilmox 25 %” – by 5–46 % relative to control. The hematocrit value was less than the control indicator by 8 % in chickens that were treated with Poledoxin after 6 days of experiment (p< 0,05) in chickens that were used with tilmox 25 % – by 10 % (p< 0,05) through 6 and 9 days of experience. The hemoglobin content in the blood of poultry of the studied groups one day after drinking antibiotic solutions was less than the control by 7 and 8 %, respectively (p< 0,05, p< 0,01), and after 4 days – by 11 and 10 % (p< 0,01). Under the infl uence of Pledoxin, the volume of 1 erythrocyte (MCV, μm 3) in the blood of chickens was less than the control by 23–39 % (p< 0,05, p< 0,01), and when exposed to tilmox 25% – by 16–35 % (p< 0,01). The hemoglobin content in 1 erythrocyte (MCH, pg) was 62–83 % of the control index when exposed to Poledoxin (p< 0,01) and 69–86 % when exposed to tylmox 25 % (p< 0,01). The number of leukocytes in the blood of a bird under the infl uence of “Poledoxin” decreased by 8 % after a day (p< 0,01), and increased by 6 and 7 % after 3 and 4 days (p< 0,01). A decrease in the number of leukocytes in the blood of chickens of both research groups by 5–11 % (p< 0,001, p< 0,01) was established after 8 and 9 days.http://nvvm.btsau.edu.ua/sites/all/modules/pubdlcnt/pubdlcnt.php?fid=1010poledoxintilmox 25 %broiler chickensred blood cellshematocrithemoglobinwhite blood cells
spellingShingle Tyshkivskaya A.
V. Dukhnitsky
Tyshkivsky M.
The eff ect of poliodoxin and tilmox 25% on the morphological and biochemical parameters of the blood of broiler chickens
Науковий вісник ветеринарної медицини
poledoxin
tilmox 25 %
broiler chickens
red blood cells
hematocrit
hemoglobin
white blood cells
title The eff ect of poliodoxin and tilmox 25% on the morphological and biochemical parameters of the blood of broiler chickens
title_full The eff ect of poliodoxin and tilmox 25% on the morphological and biochemical parameters of the blood of broiler chickens
title_fullStr The eff ect of poliodoxin and tilmox 25% on the morphological and biochemical parameters of the blood of broiler chickens
title_full_unstemmed The eff ect of poliodoxin and tilmox 25% on the morphological and biochemical parameters of the blood of broiler chickens
title_short The eff ect of poliodoxin and tilmox 25% on the morphological and biochemical parameters of the blood of broiler chickens
title_sort eff ect of poliodoxin and tilmox 25 on the morphological and biochemical parameters of the blood of broiler chickens
topic poledoxin
tilmox 25 %
broiler chickens
red blood cells
hematocrit
hemoglobin
white blood cells
url http://nvvm.btsau.edu.ua/sites/all/modules/pubdlcnt/pubdlcnt.php?fid=1010
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