Accuracy of real-time respiratory motion tracking and time delay of gating radiotherapy based on optical surface imaging technique
Abstract Background Surface-guided radiation therapy (SGRT) employs a non-invasive real-time optical surface imaging (OSI) technique for patient surface motion monitoring during radiotherapy. The main purpose of this study is to verify the real-time tracking accuracy of SGRT for respiratory motion a...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-07-01
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| Series: | Radiation Oncology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13014-020-01611-6 |
| _version_ | 1819063650602713088 |
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| author | Li Chen Sen Bai Guangjun Li Zhibin Li Qing Xiao Long Bai Changhu Li Lixun Xian Zhenyao Hu Guyu Dai Guangyu Wang |
| author_facet | Li Chen Sen Bai Guangjun Li Zhibin Li Qing Xiao Long Bai Changhu Li Lixun Xian Zhenyao Hu Guyu Dai Guangyu Wang |
| author_sort | Li Chen |
| collection | DOAJ |
| description | Abstract Background Surface-guided radiation therapy (SGRT) employs a non-invasive real-time optical surface imaging (OSI) technique for patient surface motion monitoring during radiotherapy. The main purpose of this study is to verify the real-time tracking accuracy of SGRT for respiratory motion and provide a fitting method to detect the time delay of gating. Methods A respiratory motion phantom was utilized to simulate respiratory motion using 17 cosine breathing pattern curves with various periods and amplitudes. The motion tracking of the phantom was performed by the Catalyst™ system. The tracking accuracy of the system (with period and amplitude variations) was evaluated by analyzing the adjusted coefficient of determination (A_R2) and root mean square error (RMSE). Furthermore, 13 actual respiratory curves, which were categorized into regular and irregular patterns, were selected and then simulated by the phantom. The Fourier transform was applied to the respiratory curves, and tracking accuracy was compared through the quantitative analyses of curve similarity using the Pearson correlation coefficient (PCC). In addition, the time delay of amplitude-based respiratory-gating radiotherapy based on the OSI system with various beam hold times was tested using film dosimetry for the Elekta Versa-HD and Varian Edge linacs. A dose convolution-fitting method was provided to accurately measure the beam-on and beam-off time delays. Results A_R2 and RMSE for the cosine curves were 0.9990–0.9996 and 0.110–0.241 mm for periods ranging from 1 s to 10 s and 0.9990–0.9994 and 0.059–0.175 mm for amplitudes ranging from 3 mm to 15 mm. The PCC for the actual respiratory curves ranged from 0.9955 to 0.9994, which was not significantly affected by breathing patterns. For gating radiotherapy, the average beam-on and beam-off time delays were 1664 ± 72 and 25 ± 30 ms for Versa-HD and 303 ± 45 and 34 ± 25 ms for Edge, respectively. The time delay was relatively stable as the beam hold time increased. Conclusions The OSI technique provides high accuracy for respiratory motion tracking. The proposed dose convolution-fitting method can accurately measure the time delay of respiratory-gating radiotherapy. When the OSI technique is used for respiratory-gating radiotherapy, the time delay for the beam-on is considerably longer than the beam-off. |
| first_indexed | 2024-12-21T15:18:03Z |
| format | Article |
| id | doaj.art-cc21a07df01b420cade17cfc7e7703ef |
| institution | Directory Open Access Journal |
| issn | 1748-717X |
| language | English |
| last_indexed | 2024-12-21T15:18:03Z |
| publishDate | 2020-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Radiation Oncology |
| spelling | doaj.art-cc21a07df01b420cade17cfc7e7703ef2022-12-21T18:59:06ZengBMCRadiation Oncology1748-717X2020-07-011511910.1186/s13014-020-01611-6Accuracy of real-time respiratory motion tracking and time delay of gating radiotherapy based on optical surface imaging techniqueLi Chen0Sen Bai1Guangjun Li2Zhibin Li3Qing Xiao4Long Bai5Changhu Li6Lixun Xian7Zhenyao Hu8Guyu Dai9Guangyu Wang10Department of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan UniversityDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan UniversityDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan UniversityDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan UniversityDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan UniversityDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan UniversityDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan UniversityDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan UniversityDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan UniversityDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan UniversityDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan UniversityAbstract Background Surface-guided radiation therapy (SGRT) employs a non-invasive real-time optical surface imaging (OSI) technique for patient surface motion monitoring during radiotherapy. The main purpose of this study is to verify the real-time tracking accuracy of SGRT for respiratory motion and provide a fitting method to detect the time delay of gating. Methods A respiratory motion phantom was utilized to simulate respiratory motion using 17 cosine breathing pattern curves with various periods and amplitudes. The motion tracking of the phantom was performed by the Catalyst™ system. The tracking accuracy of the system (with period and amplitude variations) was evaluated by analyzing the adjusted coefficient of determination (A_R2) and root mean square error (RMSE). Furthermore, 13 actual respiratory curves, which were categorized into regular and irregular patterns, were selected and then simulated by the phantom. The Fourier transform was applied to the respiratory curves, and tracking accuracy was compared through the quantitative analyses of curve similarity using the Pearson correlation coefficient (PCC). In addition, the time delay of amplitude-based respiratory-gating radiotherapy based on the OSI system with various beam hold times was tested using film dosimetry for the Elekta Versa-HD and Varian Edge linacs. A dose convolution-fitting method was provided to accurately measure the beam-on and beam-off time delays. Results A_R2 and RMSE for the cosine curves were 0.9990–0.9996 and 0.110–0.241 mm for periods ranging from 1 s to 10 s and 0.9990–0.9994 and 0.059–0.175 mm for amplitudes ranging from 3 mm to 15 mm. The PCC for the actual respiratory curves ranged from 0.9955 to 0.9994, which was not significantly affected by breathing patterns. For gating radiotherapy, the average beam-on and beam-off time delays were 1664 ± 72 and 25 ± 30 ms for Versa-HD and 303 ± 45 and 34 ± 25 ms for Edge, respectively. The time delay was relatively stable as the beam hold time increased. Conclusions The OSI technique provides high accuracy for respiratory motion tracking. The proposed dose convolution-fitting method can accurately measure the time delay of respiratory-gating radiotherapy. When the OSI technique is used for respiratory-gating radiotherapy, the time delay for the beam-on is considerably longer than the beam-off.http://link.springer.com/article/10.1186/s13014-020-01611-6Surface-guided radiation therapyOptical surface imagingRespiratory motion trackingGating radiotherapyTime delay |
| spellingShingle | Li Chen Sen Bai Guangjun Li Zhibin Li Qing Xiao Long Bai Changhu Li Lixun Xian Zhenyao Hu Guyu Dai Guangyu Wang Accuracy of real-time respiratory motion tracking and time delay of gating radiotherapy based on optical surface imaging technique Radiation Oncology Surface-guided radiation therapy Optical surface imaging Respiratory motion tracking Gating radiotherapy Time delay |
| title | Accuracy of real-time respiratory motion tracking and time delay of gating radiotherapy based on optical surface imaging technique |
| title_full | Accuracy of real-time respiratory motion tracking and time delay of gating radiotherapy based on optical surface imaging technique |
| title_fullStr | Accuracy of real-time respiratory motion tracking and time delay of gating radiotherapy based on optical surface imaging technique |
| title_full_unstemmed | Accuracy of real-time respiratory motion tracking and time delay of gating radiotherapy based on optical surface imaging technique |
| title_short | Accuracy of real-time respiratory motion tracking and time delay of gating radiotherapy based on optical surface imaging technique |
| title_sort | accuracy of real time respiratory motion tracking and time delay of gating radiotherapy based on optical surface imaging technique |
| topic | Surface-guided radiation therapy Optical surface imaging Respiratory motion tracking Gating radiotherapy Time delay |
| url | http://link.springer.com/article/10.1186/s13014-020-01611-6 |
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