PUTATIVE PHYSIOLOGICAL MECHANISMS UNDERLYING ANALGESIC EFFECTS OF TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS)
Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that induces changes in excitability, and activation of brain neurons and neuronal circuits.It has been observed that beyond regional effects under the electrodes, tDCS also alters activity of remote interconn...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-09-01
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| Series: | Frontiers in Human Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnhum.2013.00628/full |
| _version_ | 1818034369323859968 |
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| author | Helena eKnotkova Helena eKnotkova Michael A. Nitsche Ricardo A Cruciani Ricardo A Cruciani Ricardo A Cruciani |
| author_facet | Helena eKnotkova Helena eKnotkova Michael A. Nitsche Ricardo A Cruciani Ricardo A Cruciani Ricardo A Cruciani |
| author_sort | Helena eKnotkova |
| collection | DOAJ |
| description | Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that induces changes in excitability, and activation of brain neurons and neuronal circuits.It has been observed that beyond regional effects under the electrodes, tDCS also alters activity of remote interconnected cortical and subcortical areas. This makes the tDCS stimulation technique potentially promising for modulation of pain syndromes. Indeed, utilizing specific montages, tDCS resulted in analgesic effects in experimental settings, as well as in post-operative acute pain and chronic pain syndromes. The promising evidence of tDCS-induced analgesic effects raises the challenging and complex question of potential physiologic mechanisms that underlie/mediate the accomplished pain relief. Here we present hypotheses on how the specific montages and targets for stimulation may affect the pain processing network. |
| first_indexed | 2024-12-10T06:38:04Z |
| format | Article |
| id | doaj.art-cc255998945849ffb8e6f92224d543b0 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-12-10T06:38:04Z |
| publishDate | 2013-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-cc255998945849ffb8e6f92224d543b02022-12-22T01:58:52ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612013-09-01710.3389/fnhum.2013.0062859660PUTATIVE PHYSIOLOGICAL MECHANISMS UNDERLYING ANALGESIC EFFECTS OF TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS)Helena eKnotkova0Helena eKnotkova1Michael A. Nitsche2Ricardo A Cruciani3Ricardo A Cruciani4Ricardo A Cruciani5Beth Israel Medical CenterAlbert Einstein College of MedicineGeorg-August-UniversityBeth Israel Medical CenterAlbert Einstein College of MedicineAlbert Einstein College of MedicineTranscranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that induces changes in excitability, and activation of brain neurons and neuronal circuits.It has been observed that beyond regional effects under the electrodes, tDCS also alters activity of remote interconnected cortical and subcortical areas. This makes the tDCS stimulation technique potentially promising for modulation of pain syndromes. Indeed, utilizing specific montages, tDCS resulted in analgesic effects in experimental settings, as well as in post-operative acute pain and chronic pain syndromes. The promising evidence of tDCS-induced analgesic effects raises the challenging and complex question of potential physiologic mechanisms that underlie/mediate the accomplished pain relief. Here we present hypotheses on how the specific montages and targets for stimulation may affect the pain processing network.http://journal.frontiersin.org/Journal/10.3389/fnhum.2013.00628/fullAnalgesiaPainNeuromodulationtranscranial direct current stimulation (tDCS)mechanisms |
| spellingShingle | Helena eKnotkova Helena eKnotkova Michael A. Nitsche Ricardo A Cruciani Ricardo A Cruciani Ricardo A Cruciani PUTATIVE PHYSIOLOGICAL MECHANISMS UNDERLYING ANALGESIC EFFECTS OF TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS) Frontiers in Human Neuroscience Analgesia Pain Neuromodulation transcranial direct current stimulation (tDCS) mechanisms |
| title | PUTATIVE PHYSIOLOGICAL MECHANISMS UNDERLYING ANALGESIC EFFECTS OF TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS) |
| title_full | PUTATIVE PHYSIOLOGICAL MECHANISMS UNDERLYING ANALGESIC EFFECTS OF TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS) |
| title_fullStr | PUTATIVE PHYSIOLOGICAL MECHANISMS UNDERLYING ANALGESIC EFFECTS OF TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS) |
| title_full_unstemmed | PUTATIVE PHYSIOLOGICAL MECHANISMS UNDERLYING ANALGESIC EFFECTS OF TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS) |
| title_short | PUTATIVE PHYSIOLOGICAL MECHANISMS UNDERLYING ANALGESIC EFFECTS OF TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS) |
| title_sort | putative physiological mechanisms underlying analgesic effects of transcranial direct current stimulation tdcs |
| topic | Analgesia Pain Neuromodulation transcranial direct current stimulation (tDCS) mechanisms |
| url | http://journal.frontiersin.org/Journal/10.3389/fnhum.2013.00628/full |
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