Partial connectomes of labeled dopaminergic circuits reveal non-synaptic communication and axonal remodeling after exposure to cocaine

Partial connectomes of labeled dopaminergic circuits reveal non-synaptic communication and axonal remodeling after exposure to cocaine

Dopaminergic (DA) neurons exert profound influences on behavior including addiction. However, how DA axons communicate with target neurons and how those communications change with drug exposure remains poorly understood. We leverage cell type-specific labeling with large volume serial electron micro...

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Bibliographic Details
Main Authors: Gregg Wildenberg, Anastasia Sorokina, Jessica Koranda, Alexis Monical, Chad Heer, Mark Sheffield, Xiaoxi Zhuang, Daniel McGehee, Bobby Kasthuri
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-12-01
Series:eLife
Subjects:
connectomics
dopamine
cocaine
electron microscopy
anatomy
mouse
Online Access:https://elifesciences.org/articles/71981

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