Prone position reduces the risk of patients with mild or moderate COVID-19 progressing to severe or even critical cases: a retrospective study
Abstract Background To investigate whether prone position can reduce the risk of patients with mild or moderate COVID-19 who progress to severe or critical illness. Methods The prone position group was treated in prone position on the day of admission in addition to conventional treatment. Indicator...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-08-01
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| Series: | European Journal of Medical Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40001-022-00776-y |
| _version_ | 1818084335925854208 |
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| author | Chuan-cai Xu Jia-li Xu Xiao-fei Wang Shen Meng Sheng Ye Xiao-miao Tang Wei Lei |
| author_facet | Chuan-cai Xu Jia-li Xu Xiao-fei Wang Shen Meng Sheng Ye Xiao-miao Tang Wei Lei |
| author_sort | Chuan-cai Xu |
| collection | DOAJ |
| description | Abstract Background To investigate whether prone position can reduce the risk of patients with mild or moderate COVID-19 who progress to severe or critical illness. Methods The prone position group was treated in prone position on the day of admission in addition to conventional treatment. Indicators such as saturation of pulse oximetry (SpO2), heart rate, blood pressure, respiratory rate, and prone position-related adverse events were recorded before prone ventilation, 5 min after prone position and 30 min after prone position. Meanwhile, the cases of severe and critical patients, the percentage of transformation and the final clinical outcome of this group were analyzed. Conversion rates and mortality were calculated for patients with mild or moderate COVID-19 retrieved from the database who received only conventional care without combined prone positioning as control group. Results (1) A total of 34 patients were included in prone position group. There were significant differences in SpO2 between the first 4 days after admission and the day of discharge (F = 3.17, P < 0.001). (2) The main complications were back and neck muscle soreness (55.9%), followed by abdominal distension (8.9%). (3) In control group, a total of 4873 cases of mild and moderate patients were included from 19 literatures, with an average deterioration rate of 22.7% and mortality rate of 1.7%. (4) In prone position group, there were no severe or critical transformation cases and also no death cases. The prone position group had a significantly lower deterioration rate when compared with the control group (χ2 = 9.962, P < 0.01). Conclusion Prone position improves SpO2 in patients with mild or moderate COVID-19. It can also reduce the percentage of mild or moderate patients progressing to severe or critical patients. The application of prone position is a simple, feasible, safe and effective treatment method in such patients. |
| first_indexed | 2024-12-10T19:52:16Z |
| format | Article |
| id | doaj.art-cc2d86db736c4368983f6c09696c671e |
| institution | Directory Open Access Journal |
| issn | 2047-783X |
| language | English |
| last_indexed | 2024-12-10T19:52:16Z |
| publishDate | 2022-08-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj.art-cc2d86db736c4368983f6c09696c671e2022-12-22T01:35:46ZengBMCEuropean Journal of Medical Research2047-783X2022-08-012711910.1186/s40001-022-00776-yProne position reduces the risk of patients with mild or moderate COVID-19 progressing to severe or even critical cases: a retrospective studyChuan-cai Xu0Jia-li Xu1Xiao-fei Wang2Shen Meng3Sheng Ye4Xiao-miao Tang5Wei Lei6Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow UniversityDepartment of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow UniversityDepartment of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow UniversityDepartment of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow UniversityDepartment of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow UniversityDepartment of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow UniversityDepartment of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow UniversityAbstract Background To investigate whether prone position can reduce the risk of patients with mild or moderate COVID-19 who progress to severe or critical illness. Methods The prone position group was treated in prone position on the day of admission in addition to conventional treatment. Indicators such as saturation of pulse oximetry (SpO2), heart rate, blood pressure, respiratory rate, and prone position-related adverse events were recorded before prone ventilation, 5 min after prone position and 30 min after prone position. Meanwhile, the cases of severe and critical patients, the percentage of transformation and the final clinical outcome of this group were analyzed. Conversion rates and mortality were calculated for patients with mild or moderate COVID-19 retrieved from the database who received only conventional care without combined prone positioning as control group. Results (1) A total of 34 patients were included in prone position group. There were significant differences in SpO2 between the first 4 days after admission and the day of discharge (F = 3.17, P < 0.001). (2) The main complications were back and neck muscle soreness (55.9%), followed by abdominal distension (8.9%). (3) In control group, a total of 4873 cases of mild and moderate patients were included from 19 literatures, with an average deterioration rate of 22.7% and mortality rate of 1.7%. (4) In prone position group, there were no severe or critical transformation cases and also no death cases. The prone position group had a significantly lower deterioration rate when compared with the control group (χ2 = 9.962, P < 0.01). Conclusion Prone position improves SpO2 in patients with mild or moderate COVID-19. It can also reduce the percentage of mild or moderate patients progressing to severe or critical patients. The application of prone position is a simple, feasible, safe and effective treatment method in such patients.https://doi.org/10.1186/s40001-022-00776-yCOVID-19Prone positionProne position ventilationProgressionMildModerate |
| spellingShingle | Chuan-cai Xu Jia-li Xu Xiao-fei Wang Shen Meng Sheng Ye Xiao-miao Tang Wei Lei Prone position reduces the risk of patients with mild or moderate COVID-19 progressing to severe or even critical cases: a retrospective study European Journal of Medical Research COVID-19 Prone position Prone position ventilation Progression Mild Moderate |
| title | Prone position reduces the risk of patients with mild or moderate COVID-19 progressing to severe or even critical cases: a retrospective study |
| title_full | Prone position reduces the risk of patients with mild or moderate COVID-19 progressing to severe or even critical cases: a retrospective study |
| title_fullStr | Prone position reduces the risk of patients with mild or moderate COVID-19 progressing to severe or even critical cases: a retrospective study |
| title_full_unstemmed | Prone position reduces the risk of patients with mild or moderate COVID-19 progressing to severe or even critical cases: a retrospective study |
| title_short | Prone position reduces the risk of patients with mild or moderate COVID-19 progressing to severe or even critical cases: a retrospective study |
| title_sort | prone position reduces the risk of patients with mild or moderate covid 19 progressing to severe or even critical cases a retrospective study |
| topic | COVID-19 Prone position Prone position ventilation Progression Mild Moderate |
| url | https://doi.org/10.1186/s40001-022-00776-y |
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