Nanohydroxyapatite in dentistry: A comprehensive review
Enamel, being the hardest and the highest mineralized tissue of the human body, contains nearly 96% inorganic components and 4% organic compounds and water. Dentin contains 65% inorganic components and 35% organic and water content. The translucency and white appearance of enamel are attributed to H...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-09-01
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| Series: | Saudi Dental Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1013905223001001 |
| _version_ | 1827808445859889152 |
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| author | C. Pushpalatha V.S. Gayathri S.V. Sowmya Dominic Augustine Ahmed Alamoudi Bassam Zidane Nassreen Hassan Mohammad Albar Shilpa Bhandi |
| author_facet | C. Pushpalatha V.S. Gayathri S.V. Sowmya Dominic Augustine Ahmed Alamoudi Bassam Zidane Nassreen Hassan Mohammad Albar Shilpa Bhandi |
| author_sort | C. Pushpalatha |
| collection | DOAJ |
| description | Enamel, being the hardest and the highest mineralized tissue of the human body, contains nearly 96% inorganic components and 4% organic compounds and water. Dentin contains 65% inorganic components and 35% organic and water content. The translucency and white appearance of enamel are attributed to Hydroxyapatite (HA), which constitutes the major part of the inorganic component of dental hard tissue. With the advent of nanotechnology, the application of Nanohydroxyapatite (nHA) has piqued interest in dentistry due to its excellent mechanical, physical, and chemical properties. Compared to HA, nHA is found to have superior properties such as increased solubility, high surface energy and better biocompatibility. This is due to the morphological and structural similarity of nanosized hydroxyapatite particles to tooth hydroxyapatite crystals. These nanoparticles have been incorporated into various dental formulations for different applications to ensure comprehensive oral healthcare. To prevent dental caries, several nHA based dentifrices, mouth rinsing solutions and remineralizing pastes have been developed. nHA-based materials, such as nanocomposites, nano impression materials, and nanoceramics, have proven to be very effective in restoring tooth deformities (decay, fracture, and tooth loss). The nHA coating on the surface of the dental implant helps it bind to the bone by forming a biomimetic coating. A recent innovative strategy involves using nHA to reduce dentinal hypersensitivity and to reconstruct periodontal bone defects. The purpose of the present review is to discuss the different applications of nHA in dentistry, especially in preventive and restorative dentistry, dental implantology, bleaching and dentine hypersensitivity management. |
| first_indexed | 2024-03-11T22:27:14Z |
| format | Article |
| id | doaj.art-cc2dd4c23b9b49f8af3157d9eb96f8b8 |
| institution | Directory Open Access Journal |
| issn | 1013-9052 |
| language | English |
| last_indexed | 2024-03-11T22:27:14Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Saudi Dental Journal |
| spelling | doaj.art-cc2dd4c23b9b49f8af3157d9eb96f8b82023-09-24T05:14:17ZengElsevierSaudi Dental Journal1013-90522023-09-01356741752Nanohydroxyapatite in dentistry: A comprehensive reviewC. Pushpalatha0V.S. Gayathri1S.V. Sowmya2Dominic Augustine3Ahmed Alamoudi4Bassam Zidane5Nassreen Hassan Mohammad Albar6Shilpa Bhandi7Department of Pedodontics and Preventive Dentistry, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, IndiaDepartment of Pedodontics and Preventive Dentistry, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, IndiaDepartment of Oral Pathology & Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, IndiaDepartment of Oral Pathology & Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, IndiaOral Biology Department, King Abdulaziz University, Jeddah, Saudi ArabiaRestorative Dentistry Department, King Abdulaziz University, Jeddah, Saudi ArabiaRestorative Department, Jazan University, Jazan, Saudi ArabiaCollege of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT 84095, USA; Corresponding author at: College of Dental Medicine, Roseman University of Health Sciences, South Jordan, Utah 84095, USA.Enamel, being the hardest and the highest mineralized tissue of the human body, contains nearly 96% inorganic components and 4% organic compounds and water. Dentin contains 65% inorganic components and 35% organic and water content. The translucency and white appearance of enamel are attributed to Hydroxyapatite (HA), which constitutes the major part of the inorganic component of dental hard tissue. With the advent of nanotechnology, the application of Nanohydroxyapatite (nHA) has piqued interest in dentistry due to its excellent mechanical, physical, and chemical properties. Compared to HA, nHA is found to have superior properties such as increased solubility, high surface energy and better biocompatibility. This is due to the morphological and structural similarity of nanosized hydroxyapatite particles to tooth hydroxyapatite crystals. These nanoparticles have been incorporated into various dental formulations for different applications to ensure comprehensive oral healthcare. To prevent dental caries, several nHA based dentifrices, mouth rinsing solutions and remineralizing pastes have been developed. nHA-based materials, such as nanocomposites, nano impression materials, and nanoceramics, have proven to be very effective in restoring tooth deformities (decay, fracture, and tooth loss). The nHA coating on the surface of the dental implant helps it bind to the bone by forming a biomimetic coating. A recent innovative strategy involves using nHA to reduce dentinal hypersensitivity and to reconstruct periodontal bone defects. The purpose of the present review is to discuss the different applications of nHA in dentistry, especially in preventive and restorative dentistry, dental implantology, bleaching and dentine hypersensitivity management.http://www.sciencedirect.com/science/article/pii/S1013905223001001NanohydroxyapatiteDental cariesRemineralizationHydroxyapatiteNanoparticlesDental Implantology |
| spellingShingle | C. Pushpalatha V.S. Gayathri S.V. Sowmya Dominic Augustine Ahmed Alamoudi Bassam Zidane Nassreen Hassan Mohammad Albar Shilpa Bhandi Nanohydroxyapatite in dentistry: A comprehensive review Saudi Dental Journal Nanohydroxyapatite Dental caries Remineralization Hydroxyapatite Nanoparticles Dental Implantology |
| title | Nanohydroxyapatite in dentistry: A comprehensive review |
| title_full | Nanohydroxyapatite in dentistry: A comprehensive review |
| title_fullStr | Nanohydroxyapatite in dentistry: A comprehensive review |
| title_full_unstemmed | Nanohydroxyapatite in dentistry: A comprehensive review |
| title_short | Nanohydroxyapatite in dentistry: A comprehensive review |
| title_sort | nanohydroxyapatite in dentistry a comprehensive review |
| topic | Nanohydroxyapatite Dental caries Remineralization Hydroxyapatite Nanoparticles Dental Implantology |
| url | http://www.sciencedirect.com/science/article/pii/S1013905223001001 |
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