Macro-to-micro structural proteomics: native source proteins for high-throughput crystallization.

Macro-to-micro structural proteomics: native source proteins for high-throughput crystallization.

Structural biology and structural genomics projects routinely rely on recombinantly expressed proteins, but many proteins and complexes are difficult to obtain by this approach. We investigated native source proteins for high-throughput protein crystallography applications. The Escherichia coli prot...

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Bibliographic Details
Main Authors: Monica Totir, Nathaniel Echols, Max Nanao, Christine L Gee, Alisa Moskaleva, Scott Gradia, Anthony T Iavarone, James M Berger, Andrew P May, Chloe Zubieta, Tom Alber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3290569?pdf=render

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