Molecular profiling reveals novel therapeutic targets and clonal evolution in ovarian clear cell carcinoma

Molecular profiling reveals novel therapeutic targets and clonal evolution in ovarian clear cell carcinoma

Abstract Background Ovarian clear cell carcinoma (OCCC) has a disproportionately high incidence among women in East Asia. Patients diagnosed with OCCC tend to experience worse clinical outcomes than those with high-grade serous carcinoma (HGSC) at advanced stages. The unfavorable prognosis of OCCC c...

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Detalhes bibliográficos
Principais autores: Angel Chao, Chen-Yang Huang, Willie Yu, Chiao-Yun Lin, Hao Lin, An-Shine Chao, Cheng-Tao Lin, Hung-Hsueh Chou, Kuang-Gen Huang, Huei-Jean Huang, Ting-Chang Chang, Steven G. Rozen, Ren-Chin Wu, Chyong-Huey Lai
Formato: Artigo
Idioma:English
Publicado em: BMC 2024-11-01
coleção:BMC Cancer
Assuntos:
Ovarian clear cell carcinoma
Whole-exome sequencing
Clinical actionability
TERT mutation
Mutational signature
Clonal evolution
Acesso em linha:https://doi.org/10.1186/s12885-024-13125-5

Internet

https://doi.org/10.1186/s12885-024-13125-5

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