Particulate matter and ozone might trigger deaths from chronic ischemic heart disease
Aims: To study the association between short-term exposure to air pollutants and mortality of Chronic Ischemic Heart Disease (CIHD). Methods: Using a case-crossover design, we investigated 148,443 CIHD deaths from 2015 to 2020 in Jiangsu Province, China. Exposure to six ambient pollutants, including...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651322007710 |
| _version_ | 1811214747232632832 |
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| author | Qing Chen Qi Chen Qingqing Wang Ruijun Xu Tingting Liu Yuewei Liu Zhen Ding Hong Sun |
| author_facet | Qing Chen Qi Chen Qingqing Wang Ruijun Xu Tingting Liu Yuewei Liu Zhen Ding Hong Sun |
| author_sort | Qing Chen |
| collection | DOAJ |
| description | Aims: To study the association between short-term exposure to air pollutants and mortality of Chronic Ischemic Heart Disease (CIHD). Methods: Using a case-crossover design, we investigated 148,443 CIHD deaths from 2015 to 2020 in Jiangsu Province, China. Exposure to six ambient pollutants, including PM10, PM2.5, NO2, CO, SO2, and O3, was assessed by extracting daily concentrations from validated 10 km × 10 km pollutant grids at each subject’s residential address. A conditional logistic regression approach was used to explore the exposure-response relationship with adjustment for temperature and relative humidity. We calculated the Population Attributable Fractions (PAFs) and the attributable deaths number of CIHD. Results: An increase of 10 μg/m3 in PM10 and PM2.5 exposure was associated with a 1.16% (95% CI: 0.85–1.48%) and 1.80% (1.36–2.24%) increase in CIHD mortality, respectively. A threshold value of 123 µg/m3 was identified for the association between O3 exposure and CIHD mortality. Controlling for PM2.5, each increase of 10 µg/m3 in O3 (>threshold) was statistically significantly associated with a 0.94% (0.19–1.71%) increase in CIHD mortality, however there was no association between NO2, SO2, CO exposure and CIHD mortality. Reducing PM2.5, PM10 and O3 to the WHO air quality guidelines would prevent 6.16% (95% CI: 4.70–7.58%), 4.30% (3.18–5.43%) and 1.29% (0.48–4.20%) of CIHD deaths, respectively. During the warm season, mortality and PAFs of CIHD associated with PM2.5, PM10, and O3 were significantly higher. Conclusions: Short-term exposure to ambient PM2.5, PM10, and O3 might trigger deaths from CIHD. These findings indicate that the premature deaths of CIHD patients can be alleviated by reducing exposure to polluted air. |
| first_indexed | 2024-04-12T06:09:53Z |
| format | Article |
| id | doaj.art-cc33a3497ac64c36843a3b2f8baac152 |
| institution | Directory Open Access Journal |
| issn | 0147-6513 |
| language | English |
| last_indexed | 2024-04-12T06:09:53Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ecotoxicology and Environmental Safety |
| spelling | doaj.art-cc33a3497ac64c36843a3b2f8baac1522022-12-22T03:44:45ZengElsevierEcotoxicology and Environmental Safety0147-65132022-09-01242113931Particulate matter and ozone might trigger deaths from chronic ischemic heart diseaseQing Chen0Qi Chen1Qingqing Wang2Ruijun Xu3Tingting Liu4Yuewei Liu5Zhen Ding6Hong Sun7Department of Planning and Finance, First People’s Hospital of Lianyungang City 6, Zhenhua East Road, Lianyungang, Jiangsu, 222000, ChinaDepartment of Environment and Health, Jiangsu Provincial Center for Disease Control and Prevention, 172 Jiangsu Road, Nanjing, Jiangsu, 210009, ChinaDepartment of Environment and Health, Jiangsu Provincial Center for Disease Control and Prevention, 172 Jiangsu Road, Nanjing, Jiangsu, 210009, ChinaDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, 74 Zhongshan Second Road, Guangzhou, Guangdong 510080, ChinaDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, 74 Zhongshan Second Road, Guangzhou, Guangdong 510080, ChinaDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, 74 Zhongshan Second Road, Guangzhou, Guangdong 510080, ChinaDepartment of Environment and Health, Jiangsu Provincial Center for Disease Control and Prevention, 172 Jiangsu Road, Nanjing, Jiangsu, 210009, ChinaDepartment of Environment and Health, Jiangsu Provincial Center for Disease Control and Prevention, 172 Jiangsu Road, Nanjing, Jiangsu, 210009, China; Corresponding author.Aims: To study the association between short-term exposure to air pollutants and mortality of Chronic Ischemic Heart Disease (CIHD). Methods: Using a case-crossover design, we investigated 148,443 CIHD deaths from 2015 to 2020 in Jiangsu Province, China. Exposure to six ambient pollutants, including PM10, PM2.5, NO2, CO, SO2, and O3, was assessed by extracting daily concentrations from validated 10 km × 10 km pollutant grids at each subject’s residential address. A conditional logistic regression approach was used to explore the exposure-response relationship with adjustment for temperature and relative humidity. We calculated the Population Attributable Fractions (PAFs) and the attributable deaths number of CIHD. Results: An increase of 10 μg/m3 in PM10 and PM2.5 exposure was associated with a 1.16% (95% CI: 0.85–1.48%) and 1.80% (1.36–2.24%) increase in CIHD mortality, respectively. A threshold value of 123 µg/m3 was identified for the association between O3 exposure and CIHD mortality. Controlling for PM2.5, each increase of 10 µg/m3 in O3 (>threshold) was statistically significantly associated with a 0.94% (0.19–1.71%) increase in CIHD mortality, however there was no association between NO2, SO2, CO exposure and CIHD mortality. Reducing PM2.5, PM10 and O3 to the WHO air quality guidelines would prevent 6.16% (95% CI: 4.70–7.58%), 4.30% (3.18–5.43%) and 1.29% (0.48–4.20%) of CIHD deaths, respectively. During the warm season, mortality and PAFs of CIHD associated with PM2.5, PM10, and O3 were significantly higher. Conclusions: Short-term exposure to ambient PM2.5, PM10, and O3 might trigger deaths from CIHD. These findings indicate that the premature deaths of CIHD patients can be alleviated by reducing exposure to polluted air.http://www.sciencedirect.com/science/article/pii/S0147651322007710Air pollutionMortalityChronic ischemic heart diseaseCase-crossover design |
| spellingShingle | Qing Chen Qi Chen Qingqing Wang Ruijun Xu Tingting Liu Yuewei Liu Zhen Ding Hong Sun Particulate matter and ozone might trigger deaths from chronic ischemic heart disease Ecotoxicology and Environmental Safety Air pollution Mortality Chronic ischemic heart disease Case-crossover design |
| title | Particulate matter and ozone might trigger deaths from chronic ischemic heart disease |
| title_full | Particulate matter and ozone might trigger deaths from chronic ischemic heart disease |
| title_fullStr | Particulate matter and ozone might trigger deaths from chronic ischemic heart disease |
| title_full_unstemmed | Particulate matter and ozone might trigger deaths from chronic ischemic heart disease |
| title_short | Particulate matter and ozone might trigger deaths from chronic ischemic heart disease |
| title_sort | particulate matter and ozone might trigger deaths from chronic ischemic heart disease |
| topic | Air pollution Mortality Chronic ischemic heart disease Case-crossover design |
| url | http://www.sciencedirect.com/science/article/pii/S0147651322007710 |
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