Combination microRNA-based cellular reprogramming with paclitaxel enhances therapeutic efficacy in a relapsed and multidrug-resistant model of epithelial ovarian cancer

Combination microRNA-based cellular reprogramming with paclitaxel enhances therapeutic efficacy in a relapsed and multidrug-resistant model of epithelial ovarian cancer

Most advanced-stage ovarian cancer patients, including those with epithelial ovarian cancer (EOC), develop recurrent disease and acquisition of resistance to chemotherapy, leading to limited treatment options. Decrease in Let7b miRNA levels in clinical ovarian cancer has been associated with chemore...

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Bibliographic Details
Main Authors:	Srujan K. Gandham, Mounika Rao, Aayushi Shah, Malav S. Trivedi, Mansoor M. Amiji
Format:	Article
Language:	English
Published:	Elsevier 2022-06-01
Series:	Molecular Therapy: Oncolytics
Subjects:	ovarian cancer IDG-VEGF relapsed/MDR model microRNA-Let7b hyaluronic-acid-based nanoparticles
Online Access:	http://www.sciencedirect.com/science/article/pii/S237277052200047X

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