Anti-Osteoporosis Effect of <i>Perilla frutescens</i> Leaf Hexane Fraction through Regulating Osteoclast and Osteoblast Differentiation

Anti-Osteoporosis Effect of <i>Perilla frutescens</i> Leaf Hexane Fraction through Regulating Osteoclast and Osteoblast Differentiation

Osteoporosis is the result of an imbalance in the bone-remodeling process via an increase in osteoclastic activity and a decrease in osteoblastic activity. Our previous studies have shown that <i>Perilla frutescens</i> seed meal has anti-osteoclastogenic activity. However, the role of pe...

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Bibliographic Details
Main Authors: Kanokkarn Phromnoi, Supachai Yodkeeree, Komsak Pintha, Sariya Mapoung, Maitree Suttajit, Chalermpong Saenjum, Pornngarm Dejkriengkraikul
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
<i>Perilla frutescens</i>
osteoporosis
osteoclast
osteoblast
RANKL
TNF-α
Online Access:https://www.mdpi.com/1420-3049/27/3/824

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