Salivary gland Cytology, the new and the Old, a Pattern-Based approach
Salivary gland neoplasms are rare and represent a diverse group of tumors. Fine-needle aspiration is a cost effective approach that has been widely applied in preoperative diagnosis of salivary gland lesions to guide clinical management. The wide diversity of entities, significant morphological over...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-06-01
|
| Series: | Human Pathology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772736X24000148 |
| _version_ | 1797198811927412736 |
|---|---|
| author | Shuo Niu Yanjun Hou |
| author_facet | Shuo Niu Yanjun Hou |
| author_sort | Shuo Niu |
| collection | DOAJ |
| description | Salivary gland neoplasms are rare and represent a diverse group of tumors. Fine-needle aspiration is a cost effective approach that has been widely applied in preoperative diagnosis of salivary gland lesions to guide clinical management. The wide diversity of entities, significant morphological overlap and limited cellularity make salivary gland cytology challenging. A cellular and architectural pattern-based approach can help narrow down the differential diagnoses. In the meantime, molecular understanding has resulted in a rapid expansion and redefining of salivary gland neoplasms. Herein, we reviewed salivary gland cytology which focused on four patterns: basaloid, oncocytic/oncocytoid, mucinous/cystic/secretory and spindle, along with updated immunohistochemical and molecular features. |
| first_indexed | 2024-04-24T07:05:48Z |
| format | Article |
| id | doaj.art-cc3ac0196e1f4804bc2619152b6167b3 |
| institution | Directory Open Access Journal |
| issn | 2772-736X |
| language | English |
| last_indexed | 2024-04-24T07:05:48Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Human Pathology Reports |
| spelling | doaj.art-cc3ac0196e1f4804bc2619152b6167b32024-04-22T04:12:00ZengElsevierHuman Pathology Reports2772-736X2024-06-0136300742Salivary gland Cytology, the new and the Old, a Pattern-Based approachShuo Niu0Yanjun Hou1Department of Pathology and Laboratory Medicine, Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, NC, United StatesCorresponding author at: Department of Pathology and Laboratory Medicine, Atrium Health Wake Forest Baptist Medical Center, 1 Medical Center Boulevard, Winston-Salem, NC 27157, United States; Department of Pathology and Laboratory Medicine, Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, NC, United StatesSalivary gland neoplasms are rare and represent a diverse group of tumors. Fine-needle aspiration is a cost effective approach that has been widely applied in preoperative diagnosis of salivary gland lesions to guide clinical management. The wide diversity of entities, significant morphological overlap and limited cellularity make salivary gland cytology challenging. A cellular and architectural pattern-based approach can help narrow down the differential diagnoses. In the meantime, molecular understanding has resulted in a rapid expansion and redefining of salivary gland neoplasms. Herein, we reviewed salivary gland cytology which focused on four patterns: basaloid, oncocytic/oncocytoid, mucinous/cystic/secretory and spindle, along with updated immunohistochemical and molecular features.http://www.sciencedirect.com/science/article/pii/S2772736X24000148Salivary glandCytomorphologyMolecular |
| spellingShingle | Shuo Niu Yanjun Hou Salivary gland Cytology, the new and the Old, a Pattern-Based approach Human Pathology Reports Salivary gland Cytomorphology Molecular |
| title | Salivary gland Cytology, the new and the Old, a Pattern-Based approach |
| title_full | Salivary gland Cytology, the new and the Old, a Pattern-Based approach |
| title_fullStr | Salivary gland Cytology, the new and the Old, a Pattern-Based approach |
| title_full_unstemmed | Salivary gland Cytology, the new and the Old, a Pattern-Based approach |
| title_short | Salivary gland Cytology, the new and the Old, a Pattern-Based approach |
| title_sort | salivary gland cytology the new and the old a pattern based approach |
| topic | Salivary gland Cytomorphology Molecular |
| url | http://www.sciencedirect.com/science/article/pii/S2772736X24000148 |
| work_keys_str_mv | AT shuoniu salivaryglandcytologythenewandtheoldapatternbasedapproach AT yanjunhou salivaryglandcytologythenewandtheoldapatternbasedapproach |