Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates

Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates

Proteins from the bacterial small multidrug resistance (SMR) family are proton-coupled exporters of diverse antiseptics and antimicrobials, including polyaromatic cations and quaternary ammonium compounds. The transport mechanism of the Escherichia coli transporter, EmrE, has been studied extensivel...

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Bibliographic Details
Main Authors:	Ali A Kermani, Olive E Burata, B Ben Koff, Akiko Koide, Shohei Koide, Randy B Stockbridge
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2022-03-01
Series:	eLife
Subjects:	transporter antiseptic resistance crystallography qac
Online Access:	https://elifesciences.org/articles/76766

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