Occult Erythrocytic Membrane Damages Upon Physical and Pharmacological Exposures

The study was undertaken to develop a method for detection of occult damages to erythrocytic membranes exposed to a pulsed electric field, ionizing radiation of various nature, the blood substitute perfluorane, and some chemicals. The experimental results led to the conclusion that calibration elect...

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Bibliographic Details
Main Authors: V. V. Moroz, A. M. Chernysh, M. S. Bogushevich, Ye. K, Kozlova, U. A. Bliznyuk, P. Yu. Alekseyeva, A. P. Kozlov
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2006-12-01
Series:Общая реаниматология
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Online Access:https://www.reanimatology.com/rmt/article/view/1362
Description
Summary:The study was undertaken to develop a method for detection of occult damages to erythrocytic membranes exposed to a pulsed electric field, ionizing radiation of various nature, the blood substitute perfluorane, and some chemicals. The experimental results led to the conclusion that calibration electroporation was effective in identifying occult erythrocytic membrane damages when perfluorane was administered at different concentrations and when y-radiation was used in small doses (0.5—10 cGy). Non-additivity of the rate constants of a reduction in the suspension count of red blood cells was observed when perfluorane was added or when y-radiation and a pulsed electric field had impact on biological membranes.
ISSN:1813-9779
2411-7110