Occult Erythrocytic Membrane Damages Upon Physical and Pharmacological Exposures

The study was undertaken to develop a method for detection of occult damages to erythrocytic membranes exposed to a pulsed electric field, ionizing radiation of various nature, the blood substitute perfluorane, and some chemicals. The experimental results led to the conclusion that calibration elect...

Full description

Bibliographic Details
Main Authors: V. V. Moroz, A. M. Chernysh, M. S. Bogushevich, Ye. K, Kozlova, U. A. Bliznyuk, P. Yu. Alekseyeva, A. P. Kozlov
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2006-12-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/1362
_version_ 1826562444073369600
author V. V. Moroz
A. M. Chernysh
M. S. Bogushevich
Ye. K, Kozlova
U. A. Bliznyuk
P. Yu. Alekseyeva
A. P. Kozlov
author_facet V. V. Moroz
A. M. Chernysh
M. S. Bogushevich
Ye. K, Kozlova
U. A. Bliznyuk
P. Yu. Alekseyeva
A. P. Kozlov
author_sort V. V. Moroz
collection DOAJ
description The study was undertaken to develop a method for detection of occult damages to erythrocytic membranes exposed to a pulsed electric field, ionizing radiation of various nature, the blood substitute perfluorane, and some chemicals. The experimental results led to the conclusion that calibration electroporation was effective in identifying occult erythrocytic membrane damages when perfluorane was administered at different concentrations and when y-radiation was used in small doses (0.5—10 cGy). Non-additivity of the rate constants of a reduction in the suspension count of red blood cells was observed when perfluorane was added or when y-radiation and a pulsed electric field had impact on biological membranes.
first_indexed 2024-04-10T01:30:52Z
format Article
id doaj.art-cc43a6924e78400a8f14dd75914102ba
institution Directory Open Access Journal
issn 1813-9779
2411-7110
language English
last_indexed 2025-03-14T09:48:10Z
publishDate 2006-12-01
publisher Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
record_format Article
series Общая реаниматология
spelling doaj.art-cc43a6924e78400a8f14dd75914102ba2025-03-02T11:29:25ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102006-12-0126556010.15360/1813-9779-2006-6-55-601362Occult Erythrocytic Membrane Damages Upon Physical and Pharmacological ExposuresV. V. Moroz0A. M. Chernysh1M. S. Bogushevich2Ye. K, Kozlova3U. A. Bliznyuk4P. Yu. Alekseyeva5A. P. Kozlov6Research Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowI. M. Sechenov Moscow Medical AcademyResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowI. M. Sechenov Moscow Medical AcademyFaculty of Physics, M. V. Lomonosov Moscow State UniversityFaculty of Physics, M. V. Lomonosov Moscow State UniversityFaculty of Physics, M. V. Lomonosov Moscow State UniversityThe study was undertaken to develop a method for detection of occult damages to erythrocytic membranes exposed to a pulsed electric field, ionizing radiation of various nature, the blood substitute perfluorane, and some chemicals. The experimental results led to the conclusion that calibration electroporation was effective in identifying occult erythrocytic membrane damages when perfluorane was administered at different concentrations and when y-radiation was used in small doses (0.5—10 cGy). Non-additivity of the rate constants of a reduction in the suspension count of red blood cells was observed when perfluorane was added or when y-radiation and a pulsed electric field had impact on biological membranes.https://www.reanimatology.com/rmt/article/view/1362electroporationerythrocytic membranesperfluoraney-radiationinduced transmembrane potential
spellingShingle V. V. Moroz
A. M. Chernysh
M. S. Bogushevich
Ye. K, Kozlova
U. A. Bliznyuk
P. Yu. Alekseyeva
A. P. Kozlov
Occult Erythrocytic Membrane Damages Upon Physical and Pharmacological Exposures
Общая реаниматология
electroporation
erythrocytic membranes
perfluorane
y-radiation
induced transmembrane potential
title Occult Erythrocytic Membrane Damages Upon Physical and Pharmacological Exposures
title_full Occult Erythrocytic Membrane Damages Upon Physical and Pharmacological Exposures
title_fullStr Occult Erythrocytic Membrane Damages Upon Physical and Pharmacological Exposures
title_full_unstemmed Occult Erythrocytic Membrane Damages Upon Physical and Pharmacological Exposures
title_short Occult Erythrocytic Membrane Damages Upon Physical and Pharmacological Exposures
title_sort occult erythrocytic membrane damages upon physical and pharmacological exposures
topic electroporation
erythrocytic membranes
perfluorane
y-radiation
induced transmembrane potential
url https://www.reanimatology.com/rmt/article/view/1362
work_keys_str_mv AT vvmoroz occulterythrocyticmembranedamagesuponphysicalandpharmacologicalexposures
AT amchernysh occulterythrocyticmembranedamagesuponphysicalandpharmacologicalexposures
AT msbogushevich occulterythrocyticmembranedamagesuponphysicalandpharmacologicalexposures
AT yekkozlova occulterythrocyticmembranedamagesuponphysicalandpharmacologicalexposures
AT uabliznyuk occulterythrocyticmembranedamagesuponphysicalandpharmacologicalexposures
AT pyualekseyeva occulterythrocyticmembranedamagesuponphysicalandpharmacologicalexposures
AT apkozlov occulterythrocyticmembranedamagesuponphysicalandpharmacologicalexposures