Radiotherapy treatment planning: Benefits of CT-MR image registration and fusion in tumor volume delineation
Background/Aim. Development of imaging techniques, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), made great impact on radiotherapy treatment planning by improving the localization of target volumes. Improved localization allows better local c...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2013-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2013/0042-84501300001D.pdf |
| _version_ | 1828265420207947776 |
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| author | Đan Igor Petrović Borislava Erak Marko Nikolić Ivan Lučić Silvija |
| author_facet | Đan Igor Petrović Borislava Erak Marko Nikolić Ivan Lučić Silvija |
| author_sort | Đan Igor |
| collection | DOAJ |
| description | Background/Aim. Development of imaging techniques, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), made great impact on radiotherapy treatment planning by improving the localization of target volumes. Improved localization allows better local control of tumor volumes, but also minimizes geographical misses. Mutual information is obtained by registration and fusion of images achieved manually or automatically. The aim of this study was to validate the CT-MRI image fusion method and compare delineation obtained by CT versus CT-MRI image fusion. Methods. The image fusion software (XIO CMS 4.50.0) was applied to delineate 16 patients. The patients were scanned on CT and MRI in the treatment position within an immobilization device before the initial treatment. The gross tumor volume (GTV) and clinical target volume (CTV) were delineated on CT alone and on CT+MRI images consecutively and image fusion was obtained. Results. Image fusion showed that CTV delineated on a CT image study set is mainly inadequate for treatment planning, in comparison with CTV delineated on CT-MRI fused image study set. Fusion of different modalities enables the most accurate target volume delineation. Conclusion. This study shows that registration and image fusion allows precise target localization in terms of GTV and CTV and local disease control. |
| first_indexed | 2024-04-13T04:39:06Z |
| format | Article |
| id | doaj.art-cc4578b8c7fa44a3b2f9b0aa54a226b3 |
| institution | Directory Open Access Journal |
| issn | 0042-8450 |
| language | English |
| last_indexed | 2024-04-13T04:39:06Z |
| publishDate | 2013-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-cc4578b8c7fa44a3b2f9b0aa54a226b32022-12-22T03:02:04ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502013-01-0170873573910.2298/VSP110404001DRadiotherapy treatment planning: Benefits of CT-MR image registration and fusion in tumor volume delineationĐan IgorPetrović BorislavaErak MarkoNikolić IvanLučić SilvijaBackground/Aim. Development of imaging techniques, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), made great impact on radiotherapy treatment planning by improving the localization of target volumes. Improved localization allows better local control of tumor volumes, but also minimizes geographical misses. Mutual information is obtained by registration and fusion of images achieved manually or automatically. The aim of this study was to validate the CT-MRI image fusion method and compare delineation obtained by CT versus CT-MRI image fusion. Methods. The image fusion software (XIO CMS 4.50.0) was applied to delineate 16 patients. The patients were scanned on CT and MRI in the treatment position within an immobilization device before the initial treatment. The gross tumor volume (GTV) and clinical target volume (CTV) were delineated on CT alone and on CT+MRI images consecutively and image fusion was obtained. Results. Image fusion showed that CTV delineated on a CT image study set is mainly inadequate for treatment planning, in comparison with CTV delineated on CT-MRI fused image study set. Fusion of different modalities enables the most accurate target volume delineation. Conclusion. This study shows that registration and image fusion allows precise target localization in terms of GTV and CTV and local disease control.http://www.doiserbia.nb.rs/img/doi/0042-8450/2013/0042-84501300001D.pdfradiotherapyradiotherapy planning, computer assistedtomography, x-ray computedmagnetic resonance imaging |
| spellingShingle | Đan Igor Petrović Borislava Erak Marko Nikolić Ivan Lučić Silvija Radiotherapy treatment planning: Benefits of CT-MR image registration and fusion in tumor volume delineation Vojnosanitetski Pregled radiotherapy radiotherapy planning, computer assisted tomography, x-ray computed magnetic resonance imaging |
| title | Radiotherapy treatment planning: Benefits of CT-MR image registration and fusion in tumor volume delineation |
| title_full | Radiotherapy treatment planning: Benefits of CT-MR image registration and fusion in tumor volume delineation |
| title_fullStr | Radiotherapy treatment planning: Benefits of CT-MR image registration and fusion in tumor volume delineation |
| title_full_unstemmed | Radiotherapy treatment planning: Benefits of CT-MR image registration and fusion in tumor volume delineation |
| title_short | Radiotherapy treatment planning: Benefits of CT-MR image registration and fusion in tumor volume delineation |
| title_sort | radiotherapy treatment planning benefits of ct mr image registration and fusion in tumor volume delineation |
| topic | radiotherapy radiotherapy planning, computer assisted tomography, x-ray computed magnetic resonance imaging |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2013/0042-84501300001D.pdf |
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