Quercetin reduces hydroxyurea induced cytotoxicity in immortalized mouse aortic endothelial cells

Quercetin reduces hydroxyurea induced cytotoxicity in immortalized mouse aortic endothelial cells

Background Chronic inflammation is a characteristic of sickle cell disease (SCD), and is invariably associated with vascular endothelial injury. Hydroxyurea (HU), a naturally cytotoxic chemotherapeutic agent, is the only FDA drug approved for SCD, and is therefore naturally cytotoxic. Quercetin (QCT...

Full description

Bibliographic Details
Main Authors: Zachary M. Kiser, Monica D.M. McGee, Racquel J. Wright, Alexander Quarshie, Gale W. Newman, Karen R. Randall, Jonathan K. Stiles, Adel Driss, Jacqueline M. Hibbert
Format: Article
Language:English
Published: PeerJ Inc. 2017-05-01
Series:PeerJ
Subjects:
Quercetin
Hydroxyurea
Sickle cell disease
Vascular endothelial cells
Online Access:https://peerj.com/articles/3376.pdf

Internet

https://peerj.com/articles/3376.pdf

Similar Items