Effects of Induced Malocclusion on Vertebral Alignment in Rats: A Controlled Study by CBCTs
This study aimed to evaluate with CBCTs the alteration of vertebral alignment over time of induced malocclusion in rats. Crown pads increasing the vertical dimension of 0.5 mm were applied on the upper molars at one randomly selected side of the maxilla in rats (premature contact side) while the opp...
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| Format: | Article |
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MDPI AG
2021-09-01
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| Online Access: | https://www.mdpi.com/2076-2615/11/10/2808 |
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| author | Michele D’Attilio Gianfranco Cesaretti Paolo Viganò Karol Alí Apaza Alccayhuaman Daniele Botticelli Erick Ricardo Silva Samuel Porfirio Xavier |
| author_facet | Michele D’Attilio Gianfranco Cesaretti Paolo Viganò Karol Alí Apaza Alccayhuaman Daniele Botticelli Erick Ricardo Silva Samuel Porfirio Xavier |
| author_sort | Michele D’Attilio |
| collection | DOAJ |
| description | This study aimed to evaluate with CBCTs the alteration of vertebral alignment over time of induced malocclusion in rats. Crown pads increasing the vertical dimension of 0.5 mm were applied on the upper molars at one randomly selected side of the maxilla in rats (premature contact side) while the opposite side was left untreated (control side). Four groups were organized, ten animals each. In groups A, B, and C, the crowns were applied at time 0 (t-0). In group A, the crowns were removed after 2 weeks (t-2w) and euthanized after two more weeks, while in groups B and C, the animals were euthanized after 2 and 4 weeks (t-4w), respectively. No premature contacts were applied in group D. CBCTs were taken at t-0 in all animals before applying the crowns, at t-2w in group A before removing the crowns, and in all groups before the euthanasia. The changes in the iliac crest angle (ICA) that formed between the superior external margin of the iliac crest and the vertebral spine were evaluated. In groups A and B, after 2 weeks, the changes in ICA were statistically significant at <i>p</i> = 0.028 and <i>p</i> = 0.042, respectively. In group C, and in the control group D, the changes of ICA were not statistically significant (<i>p</i> = 0.058 and <i>p</i> = 0.414, respectively). In conclusion, the incease in monolateral occlusion in the molar region yielded a rotation of the lumbo-sacral segment towards the same side of the occlusal bite-raising. |
| first_indexed | 2024-03-10T06:47:40Z |
| format | Article |
| id | doaj.art-cc46ddb9718244298ee8b432a55420a9 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T06:47:40Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-cc46ddb9718244298ee8b432a55420a92023-11-22T17:09:26ZengMDPI AGAnimals2076-26152021-09-011110280810.3390/ani11102808Effects of Induced Malocclusion on Vertebral Alignment in Rats: A Controlled Study by CBCTsMichele D’Attilio0Gianfranco Cesaretti1Paolo Viganò2Karol Alí Apaza Alccayhuaman3Daniele Botticelli4Erick Ricardo Silva5Samuel Porfirio Xavier6Department of Innovative Technology in Medicine and Dentistry, University of Chieti-Pescara, 66100 Chieti, ItalyPrivate Practice, Castelfidardo, 60022 Ancona, ItalyARDEC Academy, 47923 Rimini, ItalyARDEC Academy, 47923 Rimini, ItalyARDEC Academy, 47923 Rimini, ItalyDepto CTBMF e Periodontia FORP-USP, Faculty of Ribeirão Preto (SP), 14000-000 Ribeirão Preto, BrazilDepto CTBMF e Periodontia FORP-USP, Faculty of Ribeirão Preto (SP), 14000-000 Ribeirão Preto, BrazilThis study aimed to evaluate with CBCTs the alteration of vertebral alignment over time of induced malocclusion in rats. Crown pads increasing the vertical dimension of 0.5 mm were applied on the upper molars at one randomly selected side of the maxilla in rats (premature contact side) while the opposite side was left untreated (control side). Four groups were organized, ten animals each. In groups A, B, and C, the crowns were applied at time 0 (t-0). In group A, the crowns were removed after 2 weeks (t-2w) and euthanized after two more weeks, while in groups B and C, the animals were euthanized after 2 and 4 weeks (t-4w), respectively. No premature contacts were applied in group D. CBCTs were taken at t-0 in all animals before applying the crowns, at t-2w in group A before removing the crowns, and in all groups before the euthanasia. The changes in the iliac crest angle (ICA) that formed between the superior external margin of the iliac crest and the vertebral spine were evaluated. In groups A and B, after 2 weeks, the changes in ICA were statistically significant at <i>p</i> = 0.028 and <i>p</i> = 0.042, respectively. In group C, and in the control group D, the changes of ICA were not statistically significant (<i>p</i> = 0.058 and <i>p</i> = 0.414, respectively). In conclusion, the incease in monolateral occlusion in the molar region yielded a rotation of the lumbo-sacral segment towards the same side of the occlusal bite-raising.https://www.mdpi.com/2076-2615/11/10/2808occlusionvertebral alignmentocclusal splintradiographyposturerats |
| spellingShingle | Michele D’Attilio Gianfranco Cesaretti Paolo Viganò Karol Alí Apaza Alccayhuaman Daniele Botticelli Erick Ricardo Silva Samuel Porfirio Xavier Effects of Induced Malocclusion on Vertebral Alignment in Rats: A Controlled Study by CBCTs Animals occlusion vertebral alignment occlusal splint radiography posture rats |
| title | Effects of Induced Malocclusion on Vertebral Alignment in Rats: A Controlled Study by CBCTs |
| title_full | Effects of Induced Malocclusion on Vertebral Alignment in Rats: A Controlled Study by CBCTs |
| title_fullStr | Effects of Induced Malocclusion on Vertebral Alignment in Rats: A Controlled Study by CBCTs |
| title_full_unstemmed | Effects of Induced Malocclusion on Vertebral Alignment in Rats: A Controlled Study by CBCTs |
| title_short | Effects of Induced Malocclusion on Vertebral Alignment in Rats: A Controlled Study by CBCTs |
| title_sort | effects of induced malocclusion on vertebral alignment in rats a controlled study by cbcts |
| topic | occlusion vertebral alignment occlusal splint radiography posture rats |
| url | https://www.mdpi.com/2076-2615/11/10/2808 |
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