Case series of three different scenarios with drug-induced Brugada patterns: fact or fiction?

Brugada syndrome is an inherited cardiac arrhythmia condition characterized by coved-type ST elevation and J point elevation of at least 2 mm in at least 2 of the right precordial electrocardiogram (ECG) leads (V1–3). An increasing number of noncardiac agents, including psychotropic and anesthetic d...

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Main Authors: Serkan Asil, Uğur Canpolat, Ergün Barış Kaya, Kudret Aytemir, Giray Kabakçı
Format: Article
Language:English
Published: KARE Publishing 2017-10-01
Series:Türk Kardiyoloji Derneği Arşivi
Subjects:
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-02717
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author Serkan Asil
Uğur Canpolat
Ergün Barış Kaya
Kudret Aytemir
Giray Kabakçı
author_facet Serkan Asil
Uğur Canpolat
Ergün Barış Kaya
Kudret Aytemir
Giray Kabakçı
author_sort Serkan Asil
collection DOAJ
description Brugada syndrome is an inherited cardiac arrhythmia condition characterized by coved-type ST elevation and J point elevation of at least 2 mm in at least 2 of the right precordial electrocardiogram (ECG) leads (V1–3). An increasing number of noncardiac agents, including psychotropic and anesthetic drugs, have been shown to induce a characteristic Brugada ECG pattern, predisposing the patient to fatal ventricular arrhythmias. However, there are scarce data regarding the clinical significance. In this case series, a typical Brugada pattern was unmasked by lithium, valproic acid, and thiocolchicoside; however, the clinical scenario was different in all 3 cases, ranging from an asymptomatic patient to sudden cardiac arrest.
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spelling doaj.art-cc47c057fce9418eb9a479f7b394ac272023-02-15T16:13:49ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692017-10-0145765065410.5543/tkda.2017.02717TKDA-02717Case series of three different scenarios with drug-induced Brugada patterns: fact or fiction?Serkan Asil0Uğur Canpolat1Ergün Barış Kaya2Kudret Aytemir3Giray Kabakçı4Department of Cardiology, Gülhane Training and Research Hospital, Ankara, TurkeyDepartment of Cardiology, Hacettepe University Faculty of Medicine, Ankara, TurkeyDepartment of Cardiology, Hacettepe University Faculty of Medicine, Ankara, TurkeyDepartment of Cardiology, Hacettepe University Faculty of Medicine, Ankara, TurkeyDepartment of Cardiology, Hacettepe University Faculty of Medicine, Ankara, TurkeyBrugada syndrome is an inherited cardiac arrhythmia condition characterized by coved-type ST elevation and J point elevation of at least 2 mm in at least 2 of the right precordial electrocardiogram (ECG) leads (V1–3). An increasing number of noncardiac agents, including psychotropic and anesthetic drugs, have been shown to induce a characteristic Brugada ECG pattern, predisposing the patient to fatal ventricular arrhythmias. However, there are scarce data regarding the clinical significance. In this case series, a typical Brugada pattern was unmasked by lithium, valproic acid, and thiocolchicoside; however, the clinical scenario was different in all 3 cases, ranging from an asymptomatic patient to sudden cardiac arrest.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-02717brugada syndromedrug-induced; electrocardiography.
spellingShingle Serkan Asil
Uğur Canpolat
Ergün Barış Kaya
Kudret Aytemir
Giray Kabakçı
Case series of three different scenarios with drug-induced Brugada patterns: fact or fiction?
Türk Kardiyoloji Derneği Arşivi
brugada syndrome
drug-induced; electrocardiography.
title Case series of three different scenarios with drug-induced Brugada patterns: fact or fiction?
title_full Case series of three different scenarios with drug-induced Brugada patterns: fact or fiction?
title_fullStr Case series of three different scenarios with drug-induced Brugada patterns: fact or fiction?
title_full_unstemmed Case series of three different scenarios with drug-induced Brugada patterns: fact or fiction?
title_short Case series of three different scenarios with drug-induced Brugada patterns: fact or fiction?
title_sort case series of three different scenarios with drug induced brugada patterns fact or fiction
topic brugada syndrome
drug-induced; electrocardiography.
url https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-02717
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AT ergunbarıskaya caseseriesofthreedifferentscenarioswithdruginducedbrugadapatternsfactorfiction
AT kudretaytemir caseseriesofthreedifferentscenarioswithdruginducedbrugadapatternsfactorfiction
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