Molecular combing and its application in clinical settings

Abstract Molecular combing technology (MCT) is an effective means for stretching DNA molecules and making them thus accessible for in situ studies. MCT uses the force exerted in the process of liquid flow via surface tension to stretch DNA molecules and spread them on solid surfaces, i.e. glass cove...

Full description

Bibliographic Details
Main Authors: Yiping Wang, Kishore Ramesh Kumar, Thomas Liehr
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Molecular Cytogenetics
Subjects:
Online Access:https://doi.org/10.1186/s13039-022-00628-8