Beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, attenuates anxiety-related behavior in a rodent post-traumatic stress disorder model

Beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, attenuates anxiety-related behavior in a rodent post-traumatic stress disorder model

Abstract Accumulating evidence suggests that elevated inflammation contributes to the pathophysiology of post-traumatic stress disorder (PTSD) and that anti-inflammatory drugs might be a new treatment strategy for PTSD. It has been reported that beta-hydroxybutyrate (BHB), one of the main ketone bod...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Takehiko Yamanashi, Masaaki Iwata, Midori Shibushita, Kyohei Tsunetomi, Mayu Nagata, Naofumi Kajitani, Akihiko Miura, Ryoichi Matsuo, Tsuyoshi Nishiguchi, Takahiro A. Kato, Daiki Setoyama, Yukihiko Shirayama, Ken Watanabe, Gen Shinozaki, Koichi Kaneko
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Nature Portfolio 2020-12-01
Цуврал:Scientific Reports
Онлайн хандалт:https://doi.org/10.1038/s41598-020-78410-2

Интернэт

https://doi.org/10.1038/s41598-020-78410-2

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