SARS-CoV-2: vaccines in the pandemic era
Abstract Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused millions of infections and deaths worldwide since its emergence in December 2019. As there is little or no natural immunity in the human population or specific anti-CO...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-01-01
|
| Series: | Military Medical Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40779-020-00296-y |
| _version_ | 1819279025356406784 |
|---|---|
| author | Dan-Dan Li Qi-Han Li |
| author_facet | Dan-Dan Li Qi-Han Li |
| author_sort | Dan-Dan Li |
| collection | DOAJ |
| description | Abstract Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused millions of infections and deaths worldwide since its emergence in December 2019. As there is little or no natural immunity in the human population or specific anti-COVID-19 drugs, researchers from the government, academia and industry are developing vaccines at an unprecedented speed to halt the pandemic. In this review, the results of animal experiments and clinical trials on several vaccine technical platforms are summarized, and several challenges are also discussed to further promote the development, evaluation and application of vaccines during the challenging situation of the global pandemic. |
| first_indexed | 2024-12-24T00:21:20Z |
| format | Article |
| id | doaj.art-cc50baf4083d418687482ce340f904e0 |
| institution | Directory Open Access Journal |
| issn | 2054-9369 |
| language | English |
| last_indexed | 2024-12-24T00:21:20Z |
| publishDate | 2021-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Military Medical Research |
| spelling | doaj.art-cc50baf4083d418687482ce340f904e02022-12-21T17:24:35ZengBMCMilitary Medical Research2054-93692021-01-018111510.1186/s40779-020-00296-ySARS-CoV-2: vaccines in the pandemic eraDan-Dan Li0Qi-Han Li1Institute of Medical Biology, Chinese Academy of Medicine Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious DiseasesInstitute of Medical Biology, Chinese Academy of Medicine Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious DiseasesAbstract Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused millions of infections and deaths worldwide since its emergence in December 2019. As there is little or no natural immunity in the human population or specific anti-COVID-19 drugs, researchers from the government, academia and industry are developing vaccines at an unprecedented speed to halt the pandemic. In this review, the results of animal experiments and clinical trials on several vaccine technical platforms are summarized, and several challenges are also discussed to further promote the development, evaluation and application of vaccines during the challenging situation of the global pandemic.https://doi.org/10.1186/s40779-020-00296-ySARS-CoV-2COVID-19VaccineVaccine candidateClinical trials |
| spellingShingle | Dan-Dan Li Qi-Han Li SARS-CoV-2: vaccines in the pandemic era Military Medical Research SARS-CoV-2 COVID-19 Vaccine Vaccine candidate Clinical trials |
| title | SARS-CoV-2: vaccines in the pandemic era |
| title_full | SARS-CoV-2: vaccines in the pandemic era |
| title_fullStr | SARS-CoV-2: vaccines in the pandemic era |
| title_full_unstemmed | SARS-CoV-2: vaccines in the pandemic era |
| title_short | SARS-CoV-2: vaccines in the pandemic era |
| title_sort | sars cov 2 vaccines in the pandemic era |
| topic | SARS-CoV-2 COVID-19 Vaccine Vaccine candidate Clinical trials |
| url | https://doi.org/10.1186/s40779-020-00296-y |
| work_keys_str_mv | AT dandanli sarscov2vaccinesinthepandemicera AT qihanli sarscov2vaccinesinthepandemicera |