Stair climbing and the incidence of atherosclerotic cardiovascular disease: a population-based prospective cohort study
Background: Stair climbing is a readily available form of physical activity with potential cardioprotective merits. Herein, we investigated the association between stair climbing and atherosclerotic cardiovascular disease (ASCVD) incidence among Japanese people. Methods: This prospective cohort stud...
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| Format: | Article |
| Language: | English |
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Komiyama Printing Co. Ltd
2023-10-01
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| Series: | Environmental Health and Preventive Medicine |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/ehpm/28/0/28_23-00166/_html/-char/en |
| _version_ | 1827778756029186048 |
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| author | Ahmed Arafa Rena Kashima Yoshihiro Kokubo |
| author_facet | Ahmed Arafa Rena Kashima Yoshihiro Kokubo |
| author_sort | Ahmed Arafa |
| collection | DOAJ |
| description | Background: Stair climbing is a readily available form of physical activity with potential cardioprotective merits. Herein, we investigated the association between stair climbing and atherosclerotic cardiovascular disease (ASCVD) incidence among Japanese people. Methods: This prospective cohort study used data from 7,282 participants, aged 30–84 years, registered in the Suita Study and free from stroke and ischemic heart disease (IHD). Standard approaches were used to detect incident ASCVD events, including cerebral infarction and IHD, during follow-up. Stair climbing was assessed using a baseline questionnaire. We applied the Cox regression to calculate the hazard ratios (HRs) and 95% confidence intervals (95% CIs) of incident ASCVD for climbing stairs in 20–39%, 40–59%, and ≥60% compared to <20% of the time. We adjusted the regression models for age, sex, body mass index, smoking, alcohol consumption, physical activity, hypertension, diabetes, atrial fibrillation, lipid profile, chronic kidney disease, and history of cardiac murmur or valvular diseases. Results: A total of 536 new ASCVD events were detected within a median follow-up period of 16.6 years. In the age- and sex-adjusted model, stair climbing 20–39%, 40–59%, and ≥60% of the time was associated with lower ASCVD incidence: HRs (95% CIs) = 0.72 (0.56, 0.92), 0.86 (0.68, 1.08), and 0.78 (0.61, 0.99), respectively (p-trend = 0.020). The corresponding associations were attenuated after adjusting for lifestyle and clinical factors: HRs (95% CIs) = 0.74 (0.58, 0.95), 0.90 (0.71, 1.13), and 0.89 (0.69, 1.13), respectively (p-trend = 0.152). Conclusion: Frequent stair climbing was associated with lower ASCVD incidence; however, this association was partly explained by lifestyle and clinical factors of participants. |
| first_indexed | 2024-03-11T14:38:24Z |
| format | Article |
| id | doaj.art-cc539ddaa633484d9e39d13937e6add5 |
| institution | Directory Open Access Journal |
| issn | 1342-078X 1347-4715 |
| language | English |
| last_indexed | 2024-03-11T14:38:24Z |
| publishDate | 2023-10-01 |
| publisher | Komiyama Printing Co. Ltd |
| record_format | Article |
| series | Environmental Health and Preventive Medicine |
| spelling | doaj.art-cc539ddaa633484d9e39d13937e6add52023-10-30T23:52:31ZengKomiyama Printing Co. LtdEnvironmental Health and Preventive Medicine1342-078X1347-47152023-10-0128606010.1265/ehpm.23-00166ehpmStair climbing and the incidence of atherosclerotic cardiovascular disease: a population-based prospective cohort studyAhmed Arafa0https://orcid.org/0000-0002-3335-2243Rena Kashima1Yoshihiro Kokubo2https://orcid.org/0000-0002-0705-9449Department of Preventive Cardiology, National Cerebral and Cardiovascular CenterDepartment of Preventive Cardiology, National Cerebral and Cardiovascular CenterDepartment of Preventive Cardiology, National Cerebral and Cardiovascular CenterBackground: Stair climbing is a readily available form of physical activity with potential cardioprotective merits. Herein, we investigated the association between stair climbing and atherosclerotic cardiovascular disease (ASCVD) incidence among Japanese people. Methods: This prospective cohort study used data from 7,282 participants, aged 30–84 years, registered in the Suita Study and free from stroke and ischemic heart disease (IHD). Standard approaches were used to detect incident ASCVD events, including cerebral infarction and IHD, during follow-up. Stair climbing was assessed using a baseline questionnaire. We applied the Cox regression to calculate the hazard ratios (HRs) and 95% confidence intervals (95% CIs) of incident ASCVD for climbing stairs in 20–39%, 40–59%, and ≥60% compared to <20% of the time. We adjusted the regression models for age, sex, body mass index, smoking, alcohol consumption, physical activity, hypertension, diabetes, atrial fibrillation, lipid profile, chronic kidney disease, and history of cardiac murmur or valvular diseases. Results: A total of 536 new ASCVD events were detected within a median follow-up period of 16.6 years. In the age- and sex-adjusted model, stair climbing 20–39%, 40–59%, and ≥60% of the time was associated with lower ASCVD incidence: HRs (95% CIs) = 0.72 (0.56, 0.92), 0.86 (0.68, 1.08), and 0.78 (0.61, 0.99), respectively (p-trend = 0.020). The corresponding associations were attenuated after adjusting for lifestyle and clinical factors: HRs (95% CIs) = 0.74 (0.58, 0.95), 0.90 (0.71, 1.13), and 0.89 (0.69, 1.13), respectively (p-trend = 0.152). Conclusion: Frequent stair climbing was associated with lower ASCVD incidence; however, this association was partly explained by lifestyle and clinical factors of participants.https://www.jstage.jst.go.jp/article/ehpm/28/0/28_23-00166/_html/-char/enstair climbingascvdprospective cohortpopulation-based study |
| spellingShingle | Ahmed Arafa Rena Kashima Yoshihiro Kokubo Stair climbing and the incidence of atherosclerotic cardiovascular disease: a population-based prospective cohort study Environmental Health and Preventive Medicine stair climbing ascvd prospective cohort population-based study |
| title | Stair climbing and the incidence of atherosclerotic cardiovascular disease: a population-based prospective cohort study |
| title_full | Stair climbing and the incidence of atherosclerotic cardiovascular disease: a population-based prospective cohort study |
| title_fullStr | Stair climbing and the incidence of atherosclerotic cardiovascular disease: a population-based prospective cohort study |
| title_full_unstemmed | Stair climbing and the incidence of atherosclerotic cardiovascular disease: a population-based prospective cohort study |
| title_short | Stair climbing and the incidence of atherosclerotic cardiovascular disease: a population-based prospective cohort study |
| title_sort | stair climbing and the incidence of atherosclerotic cardiovascular disease a population based prospective cohort study |
| topic | stair climbing ascvd prospective cohort population-based study |
| url | https://www.jstage.jst.go.jp/article/ehpm/28/0/28_23-00166/_html/-char/en |
| work_keys_str_mv | AT ahmedarafa stairclimbingandtheincidenceofatheroscleroticcardiovasculardiseaseapopulationbasedprospectivecohortstudy AT renakashima stairclimbingandtheincidenceofatheroscleroticcardiovasculardiseaseapopulationbasedprospectivecohortstudy AT yoshihirokokubo stairclimbingandtheincidenceofatheroscleroticcardiovasculardiseaseapopulationbasedprospectivecohortstudy |