In Vitro Biodegradation of a-C:H:SiO<sub>x</sub> Films on Ti-6Al-4V Alloy
This paper focuses mainly on the in vitro study of a five-week biodegradation of a-C:H:SiO<sub>x</sub> films of different thickness, obtained by plasma-assisted chemical vapor deposition onto Ti-6Al-4V alloy substrate using its pulsed bipolar biasing. In vitro immersion of a-C:H:SiO<s...
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2022-06-01
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| Online Access: | https://www.mdpi.com/1996-1944/15/12/4239 |
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| author | Alexander Grenadyorov Andrey Solovyev Konstantin Oskomov Ekaterina Porokhova Konstantin Brazovskii Anna Gorokhova Temur Nasibov Larisa Litvinova Igor Khlusov |
| author_facet | Alexander Grenadyorov Andrey Solovyev Konstantin Oskomov Ekaterina Porokhova Konstantin Brazovskii Anna Gorokhova Temur Nasibov Larisa Litvinova Igor Khlusov |
| author_sort | Alexander Grenadyorov |
| collection | DOAJ |
| description | This paper focuses mainly on the in vitro study of a five-week biodegradation of a-C:H:SiO<sub>x</sub> films of different thickness, obtained by plasma-assisted chemical vapor deposition onto Ti-6Al-4V alloy substrate using its pulsed bipolar biasing. In vitro immersion of a-C:H:SiO<sub>x</sub> films in a solution of 0.9% NaCl was used. It is shown how the a-C:H:SiO<sub>x</sub> film thickness (0.5–3 µm) affects the surface morphology, adhesive strength, and Na<sup>+</sup> and Cl<sup>−</sup> precipitation on the film surface from the NaCl solution. With increasing film thickness, the roughness indices are reducing a little. The adhesive strength of the a-C:H:SiO<sub>x</sub> films to metal substrate corresponds to quality HF1 (0.5 µm in thickness) and HF2-HF3 (1.5–3 µm in thickness) of the Rockwell hardness test (VDI 3198) that defines strong interfacial adhesion and is usually applied in practice. The morphometric analysis of the film surface shows that on a-C:H:SiO<sub>x</sub>-coated Ti-6Al-4V alloy surface, the area occupied by the grains of sodium chloride is lower than on the uncoated surface. The reduction in the ion precipitation from 0.9% NaCl onto the film surface depended on the elemental composition of the surface layer conditioned by the thickness growth of the a-C:H:SiO<sub>x</sub> film. Based on the results of energy dispersive X-ray spectroscopy, the multiple regression equations are suggested to explain the effect of the elemental composition of the a-C:H:SiO<sub>x</sub> film on the decreased Na<sup>+</sup> and Cl<sup>−</sup> precipitation. As a result, the a-C:H:SiO<sub>x</sub> films successfully combine good adhesion strength and rare ion precipitation and thus are rather promising for medical applications on cardiovascular stents and/or friction parts of heart pumps. |
| first_indexed | 2024-03-09T23:11:09Z |
| format | Article |
| id | doaj.art-cc54f21a45ad4af986b0c5e910f888f5 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-09T23:11:09Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-cc54f21a45ad4af986b0c5e910f888f52023-11-23T17:45:05ZengMDPI AGMaterials1996-19442022-06-011512423910.3390/ma15124239In Vitro Biodegradation of a-C:H:SiO<sub>x</sub> Films on Ti-6Al-4V AlloyAlexander Grenadyorov0Andrey Solovyev1Konstantin Oskomov2Ekaterina Porokhova3Konstantin Brazovskii4Anna Gorokhova5Temur Nasibov6Larisa Litvinova7Igor Khlusov8The Institute of High Current Electronics SB RAS, 2/3, Akademichesky Ave., 634055 Tomsk, RussiaThe Institute of High Current Electronics SB RAS, 2/3, Akademichesky Ave., 634055 Tomsk, RussiaThe Institute of High Current Electronics SB RAS, 2/3, Akademichesky Ave., 634055 Tomsk, RussiaDepartment of Morphology and General Pathology, Siberian State Medical University, 2, Moskovskii Trakt, 634050 Tomsk, RussiaResearch School of Chemistry and Applied Biomedical Sciences, National Research Tomsk Polytechnic University, 43-A, Lenin Ave., 634050 Tomsk, RussiaDepartment of Morphology and General Pathology, Siberian State Medical University, 2, Moskovskii Trakt, 634050 Tomsk, RussiaDepartment of Morphology and General Pathology, Siberian State Medical University, 2, Moskovskii Trakt, 634050 Tomsk, RussiaCenter for Immunology and Cellular Biotechnology, Immanuel Kant Baltic Federal University, 14A, Nevskii Str., 236016 Kaliningrad, RussiaDepartment of Morphology and General Pathology, Siberian State Medical University, 2, Moskovskii Trakt, 634050 Tomsk, RussiaThis paper focuses mainly on the in vitro study of a five-week biodegradation of a-C:H:SiO<sub>x</sub> films of different thickness, obtained by plasma-assisted chemical vapor deposition onto Ti-6Al-4V alloy substrate using its pulsed bipolar biasing. In vitro immersion of a-C:H:SiO<sub>x</sub> films in a solution of 0.9% NaCl was used. It is shown how the a-C:H:SiO<sub>x</sub> film thickness (0.5–3 µm) affects the surface morphology, adhesive strength, and Na<sup>+</sup> and Cl<sup>−</sup> precipitation on the film surface from the NaCl solution. With increasing film thickness, the roughness indices are reducing a little. The adhesive strength of the a-C:H:SiO<sub>x</sub> films to metal substrate corresponds to quality HF1 (0.5 µm in thickness) and HF2-HF3 (1.5–3 µm in thickness) of the Rockwell hardness test (VDI 3198) that defines strong interfacial adhesion and is usually applied in practice. The morphometric analysis of the film surface shows that on a-C:H:SiO<sub>x</sub>-coated Ti-6Al-4V alloy surface, the area occupied by the grains of sodium chloride is lower than on the uncoated surface. The reduction in the ion precipitation from 0.9% NaCl onto the film surface depended on the elemental composition of the surface layer conditioned by the thickness growth of the a-C:H:SiO<sub>x</sub> film. Based on the results of energy dispersive X-ray spectroscopy, the multiple regression equations are suggested to explain the effect of the elemental composition of the a-C:H:SiO<sub>x</sub> film on the decreased Na<sup>+</sup> and Cl<sup>−</sup> precipitation. As a result, the a-C:H:SiO<sub>x</sub> films successfully combine good adhesion strength and rare ion precipitation and thus are rather promising for medical applications on cardiovascular stents and/or friction parts of heart pumps.https://www.mdpi.com/1996-1944/15/12/4239diamond-like nanocompositea-C:H:SiO<sub>x</sub> filmadhesionfive-week biodegradation0.9% NaCl solution |
| spellingShingle | Alexander Grenadyorov Andrey Solovyev Konstantin Oskomov Ekaterina Porokhova Konstantin Brazovskii Anna Gorokhova Temur Nasibov Larisa Litvinova Igor Khlusov In Vitro Biodegradation of a-C:H:SiO<sub>x</sub> Films on Ti-6Al-4V Alloy Materials diamond-like nanocomposite a-C:H:SiO<sub>x</sub> film adhesion five-week biodegradation 0.9% NaCl solution |
| title | In Vitro Biodegradation of a-C:H:SiO<sub>x</sub> Films on Ti-6Al-4V Alloy |
| title_full | In Vitro Biodegradation of a-C:H:SiO<sub>x</sub> Films on Ti-6Al-4V Alloy |
| title_fullStr | In Vitro Biodegradation of a-C:H:SiO<sub>x</sub> Films on Ti-6Al-4V Alloy |
| title_full_unstemmed | In Vitro Biodegradation of a-C:H:SiO<sub>x</sub> Films on Ti-6Al-4V Alloy |
| title_short | In Vitro Biodegradation of a-C:H:SiO<sub>x</sub> Films on Ti-6Al-4V Alloy |
| title_sort | in vitro biodegradation of a c h sio sub x sub films on ti 6al 4v alloy |
| topic | diamond-like nanocomposite a-C:H:SiO<sub>x</sub> film adhesion five-week biodegradation 0.9% NaCl solution |
| url | https://www.mdpi.com/1996-1944/15/12/4239 |
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