Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages

Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages

Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), especially the latest Omicron, have exhibited severe antibody evasion. Broadly neutralizing antibodies with high potency against Omicron are urgently needed for understanding the working mechanisms...

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Bibliographic Details
Main Authors: Xiaoman Li, Yongbing Pan, Qiangling Yin, Zejun Wang, Sisi Shan, Laixing Zhang, Jinfang Yu, Yuanyuan Qu, Lina Sun, Fang Gui, Jia Lu, Zhaofei Jing, Wei Wu, Tao Huang, Xuanling Shi, Jiandong Li, Xinguo Li, Dexin Li, Shiwen Wang, Maojun Yang, Linqi Zhang, Kai Duan, Mifang Liang, Xiaoming Yang, Xinquan Wang
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-022-00449-4

Internet

https://doi.org/10.1038/s41421-022-00449-4

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