Trivalent soluble TNF Receptor, a potent TNF-α antagonist for the treatment collagen-induced arthritis

Trivalent soluble TNF Receptor, a potent TNF-α antagonist for the treatment collagen-induced arthritis

Abstract Tumor necrosis factor is a major pro-inflammatory cytokine which triggers various physiological consequences by binding to and trimerizing its receptors, and has been the single most sought-after drug target for intervening autoimmune diseases such as rheumatoid arthritis and psoriasis. How...

Full description

Bibliographic Details
Main Authors: Xiaofang Cui, Linmo Chang, Youwei Li, Qianrui Lv, Fei Wang, Yaxian Lin, Weiyang Li, Jonathan D. Meade, Jamie C. Walden, Peng Liang
Format: Article
Language:English
Published: Nature Portfolio 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25652-w

Internet

https://doi.org/10.1038/s41598-018-25652-w

Similar Items