THERAPEUTIC OPPORTUNITIES OF FUNCTIONAL COMPOUND, CONTAINING LACTULOSE, IN INFANTS UNDER FIRST YEAR OF LIFE WITH INFECTIONAL ENTEROCOLITIS AND INTESTINAL DISBIOSIS

<em>This trial studied effectiveness of prebiotic dose of lactulose in 200–400 ml of milk compound «Bifidus», in nutrition of infants under first year old, hospitalized with inflectional enterocolitis. Catamnestic observation of patients with diagnostics of faecal microflora showed increase of...

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Bibliographic Details
Main Authors: E.R. Meskina, L.V. Feklistova, A.Yu. Ushakova, L.V. Pozhalostina, E.I. Likhanskaya
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2009-01-01
Series:Вопросы современной педиатрии
Online Access:http://vsp.spr-journal.ru:80/jour/article/view/1145
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Summary:<em>This trial studied effectiveness of prebiotic dose of lactulose in 200–400 ml of milk compound «Bifidus», in nutrition of infants under first year old, hospitalized with inflectional enterocolitis. Catamnestic observation of patients with diagnostics of faecal microflora showed increase of rate (on 29%) of durable stool normalization in children, whose nutrition contained of «Bifidus» compound during 1–1.5 months, compared to children, receiving compounds without prebiotic substances (p = 0.048). Besides, statistically significant increase of obligate populations of microbes in intestine of children, receiving breast feeding or lactulose-containing compound was detected. Such changes were revealed on the basis of stopping the symptoms of intestinal inflammatory process. Children, receiving compound with lactulose, showed restoration of micro biocenosis and decrease of rate of proliferation of opportunistic gram-negative pathogens.</em><br /><strong><em>Key words: children under first year old, inflectional enterocolitis, intestinal microflora, lactulose.</em></strong><br /><span style="text-decoration: underline;"><em>(<em><em><em>Voprosy sovremennoi pediatrii — </em></em></em>Current Pediatrics. 2009;8(4):<em>63-71</em>)</em></span>
ISSN:1682-5527
1682-5535