THERAPEUTIC OPPORTUNITIES OF FUNCTIONAL COMPOUND, CONTAINING LACTULOSE, IN INFANTS UNDER FIRST YEAR OF LIFE WITH INFECTIONAL ENTEROCOLITIS AND INTESTINAL DISBIOSIS

<em>This trial studied effectiveness of prebiotic dose of lactulose in 200–400 ml of milk compound «Bifidus», in nutrition of infants under first year old, hospitalized with inflectional enterocolitis. Catamnestic observation of patients with diagnostics of faecal microflora showed increase of...

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Main Authors: E.R. Meskina, L.V. Feklistova, A.Yu. Ushakova, L.V. Pozhalostina, E.I. Likhanskaya
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2009-01-01
Series:Вопросы современной педиатрии
Online Access:http://vsp.spr-journal.ru:80/jour/article/view/1145
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author E.R. Meskina
L.V. Feklistova
A.Yu. Ushakova
L.V. Pozhalostina
E.I. Likhanskaya
author_facet E.R. Meskina
L.V. Feklistova
A.Yu. Ushakova
L.V. Pozhalostina
E.I. Likhanskaya
author_sort E.R. Meskina
collection DOAJ
description <em>This trial studied effectiveness of prebiotic dose of lactulose in 200–400 ml of milk compound «Bifidus», in nutrition of infants under first year old, hospitalized with inflectional enterocolitis. Catamnestic observation of patients with diagnostics of faecal microflora showed increase of rate (on 29%) of durable stool normalization in children, whose nutrition contained of «Bifidus» compound during 1–1.5 months, compared to children, receiving compounds without prebiotic substances (p = 0.048). Besides, statistically significant increase of obligate populations of microbes in intestine of children, receiving breast feeding or lactulose-containing compound was detected. Such changes were revealed on the basis of stopping the symptoms of intestinal inflammatory process. Children, receiving compound with lactulose, showed restoration of micro biocenosis and decrease of rate of proliferation of opportunistic gram-negative pathogens.</em><br /><strong><em>Key words: children under first year old, inflectional enterocolitis, intestinal microflora, lactulose.</em></strong><br /><span style="text-decoration: underline;"><em>(<em><em><em>Voprosy sovremennoi pediatrii — </em></em></em>Current Pediatrics. 2009;8(4):<em>63-71</em>)</em></span>
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spelling doaj.art-cc6d8618195f4992b1e263e0763344e62023-09-02T15:29:47Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352009-01-018463711146THERAPEUTIC OPPORTUNITIES OF FUNCTIONAL COMPOUND, CONTAINING LACTULOSE, IN INFANTS UNDER FIRST YEAR OF LIFE WITH INFECTIONAL ENTEROCOLITIS AND INTESTINAL DISBIOSISE.R. Meskina0L.V. Feklistova1A.Yu. Ushakova2L.V. Pozhalostina3E.I. Likhanskaya4M.F. Vladimirskiy Moscow Regional Scientific Clinical InstituteM.F. Vladimirskiy Moscow Regional Scientific Clinical InstituteM.F. Vladimirskiy Moscow Regional Scientific Clinical InstituteM.F. Vladimirskiy Moscow Regional Scientific Clinical InstituteM.F. Vladimirskiy Moscow Regional Scientific Clinical Institute<em>This trial studied effectiveness of prebiotic dose of lactulose in 200–400 ml of milk compound «Bifidus», in nutrition of infants under first year old, hospitalized with inflectional enterocolitis. Catamnestic observation of patients with diagnostics of faecal microflora showed increase of rate (on 29%) of durable stool normalization in children, whose nutrition contained of «Bifidus» compound during 1–1.5 months, compared to children, receiving compounds without prebiotic substances (p = 0.048). Besides, statistically significant increase of obligate populations of microbes in intestine of children, receiving breast feeding or lactulose-containing compound was detected. Such changes were revealed on the basis of stopping the symptoms of intestinal inflammatory process. Children, receiving compound with lactulose, showed restoration of micro biocenosis and decrease of rate of proliferation of opportunistic gram-negative pathogens.</em><br /><strong><em>Key words: children under first year old, inflectional enterocolitis, intestinal microflora, lactulose.</em></strong><br /><span style="text-decoration: underline;"><em>(<em><em><em>Voprosy sovremennoi pediatrii — </em></em></em>Current Pediatrics. 2009;8(4):<em>63-71</em>)</em></span>http://vsp.spr-journal.ru:80/jour/article/view/1145
spellingShingle E.R. Meskina
L.V. Feklistova
A.Yu. Ushakova
L.V. Pozhalostina
E.I. Likhanskaya
THERAPEUTIC OPPORTUNITIES OF FUNCTIONAL COMPOUND, CONTAINING LACTULOSE, IN INFANTS UNDER FIRST YEAR OF LIFE WITH INFECTIONAL ENTEROCOLITIS AND INTESTINAL DISBIOSIS
Вопросы современной педиатрии
title THERAPEUTIC OPPORTUNITIES OF FUNCTIONAL COMPOUND, CONTAINING LACTULOSE, IN INFANTS UNDER FIRST YEAR OF LIFE WITH INFECTIONAL ENTEROCOLITIS AND INTESTINAL DISBIOSIS
title_full THERAPEUTIC OPPORTUNITIES OF FUNCTIONAL COMPOUND, CONTAINING LACTULOSE, IN INFANTS UNDER FIRST YEAR OF LIFE WITH INFECTIONAL ENTEROCOLITIS AND INTESTINAL DISBIOSIS
title_fullStr THERAPEUTIC OPPORTUNITIES OF FUNCTIONAL COMPOUND, CONTAINING LACTULOSE, IN INFANTS UNDER FIRST YEAR OF LIFE WITH INFECTIONAL ENTEROCOLITIS AND INTESTINAL DISBIOSIS
title_full_unstemmed THERAPEUTIC OPPORTUNITIES OF FUNCTIONAL COMPOUND, CONTAINING LACTULOSE, IN INFANTS UNDER FIRST YEAR OF LIFE WITH INFECTIONAL ENTEROCOLITIS AND INTESTINAL DISBIOSIS
title_short THERAPEUTIC OPPORTUNITIES OF FUNCTIONAL COMPOUND, CONTAINING LACTULOSE, IN INFANTS UNDER FIRST YEAR OF LIFE WITH INFECTIONAL ENTEROCOLITIS AND INTESTINAL DISBIOSIS
title_sort therapeutic opportunities of functional compound containing lactulose in infants under first year of life with infectional enterocolitis and intestinal disbiosis
url http://vsp.spr-journal.ru:80/jour/article/view/1145
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