Cardiovascular responses to high‐intensity stair climbing in individuals with coronary artery disease
Abstract Exercise‐based cardiac rehabilitation leads to improvements in cardiovascular function in individuals with coronary artery disease. The cardiac effects of coronary artery disease (CAD) can be quantified using clinical echocardiographic measures, such as ejection fraction (EF). Measures of c...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-05-01
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| Series: | Physiological Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.14814/phy2.15308 |
| _version_ | 1827580970611507200 |
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| author | Sydney E. Valentino Emily C. Dunford Jonathan Dubberley Eva M. Lonn Martin J. Gibala Stuart M. Phillips Maureen J. MacDonald |
| author_facet | Sydney E. Valentino Emily C. Dunford Jonathan Dubberley Eva M. Lonn Martin J. Gibala Stuart M. Phillips Maureen J. MacDonald |
| author_sort | Sydney E. Valentino |
| collection | DOAJ |
| description | Abstract Exercise‐based cardiac rehabilitation leads to improvements in cardiovascular function in individuals with coronary artery disease. The cardiac effects of coronary artery disease (CAD) can be quantified using clinical echocardiographic measures, such as ejection fraction (EF). Measures of cardiovascular function typically only used in research settings can provide additional information and maybe more sensitive indices to assess changes after exercise‐based cardiac rehabilitation. These additional measures include endothelial function (measured by flow‐mediated dilation), left ventricular twist, myocardial performance index, and global longitudinal strain. To investigate the cardiovascular response to 12 week of either traditional moderate‐intensity (TRAD) or stair climbing‐based high‐intensity interval (STAIR) exercise‐based cardiac rehabilitation using both clinical and additional measures of cardiovascular function in individuals with CAD. Measurements were made at baseline (BL) and after supervised (4wk) and unsupervised (12 week) of training. This study was registered as a clinical trial at clinicaltrials.gov (NCT03235674). Participants were randomized into either TRAD (n = 9, 8M/1F) and STAIR (n = 9, 8M/1F). There was a training‐associated increase in one component of left ventricular twist: Cardiac apical rotation (TRAD: BL: 5.6 ± 3.3º, 4 week: 8.0 ± 3.9º, 12 week: 6.2 ± 5.1º and STAIR: BL: 5.1 ± 3.6º, 4 week: 7.4 ± 3.9º, 12 week: 7.8 ± 2.8º, p (time) = 0.03, η2 = 0.20; main effect) and post‐hoc analysis revealed a difference between BL and 4 week (p = 0.02). There were no changes in any other clinical or additional measures of cardiovascular function. The small increase in cardiac apical rotation observed after 4 weeks of training may indicate an early change in cardiac function. A larger overall training stimulus may be needed to elicit other cardiovascular function changes. |
| first_indexed | 2024-03-08T22:27:47Z |
| format | Article |
| id | doaj.art-cc6e31e9d6944fd58255efdfd9bffc83 |
| institution | Directory Open Access Journal |
| issn | 2051-817X |
| language | English |
| last_indexed | 2024-03-08T22:27:47Z |
| publishDate | 2022-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Physiological Reports |
| spelling | doaj.art-cc6e31e9d6944fd58255efdfd9bffc832023-12-18T09:26:14ZengWileyPhysiological Reports2051-817X2022-05-011010n/an/a10.14814/phy2.15308Cardiovascular responses to high‐intensity stair climbing in individuals with coronary artery diseaseSydney E. Valentino0Emily C. Dunford1Jonathan Dubberley2Eva M. Lonn3Martin J. Gibala4Stuart M. Phillips5Maureen J. MacDonald6Department of Kinesiology McMaster University Hamilton Ontario CanadaDepartment of Kinesiology McMaster University Hamilton Ontario CanadaHamilton Health Sciences Hamilton Ontario CanadaHamilton Health Sciences Hamilton Ontario CanadaDepartment of Kinesiology McMaster University Hamilton Ontario CanadaDepartment of Kinesiology McMaster University Hamilton Ontario CanadaDepartment of Kinesiology McMaster University Hamilton Ontario CanadaAbstract Exercise‐based cardiac rehabilitation leads to improvements in cardiovascular function in individuals with coronary artery disease. The cardiac effects of coronary artery disease (CAD) can be quantified using clinical echocardiographic measures, such as ejection fraction (EF). Measures of cardiovascular function typically only used in research settings can provide additional information and maybe more sensitive indices to assess changes after exercise‐based cardiac rehabilitation. These additional measures include endothelial function (measured by flow‐mediated dilation), left ventricular twist, myocardial performance index, and global longitudinal strain. To investigate the cardiovascular response to 12 week of either traditional moderate‐intensity (TRAD) or stair climbing‐based high‐intensity interval (STAIR) exercise‐based cardiac rehabilitation using both clinical and additional measures of cardiovascular function in individuals with CAD. Measurements were made at baseline (BL) and after supervised (4wk) and unsupervised (12 week) of training. This study was registered as a clinical trial at clinicaltrials.gov (NCT03235674). Participants were randomized into either TRAD (n = 9, 8M/1F) and STAIR (n = 9, 8M/1F). There was a training‐associated increase in one component of left ventricular twist: Cardiac apical rotation (TRAD: BL: 5.6 ± 3.3º, 4 week: 8.0 ± 3.9º, 12 week: 6.2 ± 5.1º and STAIR: BL: 5.1 ± 3.6º, 4 week: 7.4 ± 3.9º, 12 week: 7.8 ± 2.8º, p (time) = 0.03, η2 = 0.20; main effect) and post‐hoc analysis revealed a difference between BL and 4 week (p = 0.02). There were no changes in any other clinical or additional measures of cardiovascular function. The small increase in cardiac apical rotation observed after 4 weeks of training may indicate an early change in cardiac function. A larger overall training stimulus may be needed to elicit other cardiovascular function changes.https://doi.org/10.14814/phy2.15308cardiac functioncardiac rehabilitationflow‐mediated dilationHIITstair climbing |
| spellingShingle | Sydney E. Valentino Emily C. Dunford Jonathan Dubberley Eva M. Lonn Martin J. Gibala Stuart M. Phillips Maureen J. MacDonald Cardiovascular responses to high‐intensity stair climbing in individuals with coronary artery disease Physiological Reports cardiac function cardiac rehabilitation flow‐mediated dilation HIIT stair climbing |
| title | Cardiovascular responses to high‐intensity stair climbing in individuals with coronary artery disease |
| title_full | Cardiovascular responses to high‐intensity stair climbing in individuals with coronary artery disease |
| title_fullStr | Cardiovascular responses to high‐intensity stair climbing in individuals with coronary artery disease |
| title_full_unstemmed | Cardiovascular responses to high‐intensity stair climbing in individuals with coronary artery disease |
| title_short | Cardiovascular responses to high‐intensity stair climbing in individuals with coronary artery disease |
| title_sort | cardiovascular responses to high intensity stair climbing in individuals with coronary artery disease |
| topic | cardiac function cardiac rehabilitation flow‐mediated dilation HIIT stair climbing |
| url | https://doi.org/10.14814/phy2.15308 |
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