SOD1 and amyotrophic lateral sclerosis: mutations and oligomerization.

SOD1 and amyotrophic lateral sclerosis: mutations and oligomerization.

There are about 100 single point mutations of copper, zinc superoxide dismutase 1 (SOD1) which are reported (http://alsod.iop.kcl.ac.uk/Als/index.aspx) to be related to the familial form (fALS) of amyotrophic lateral sclerosis (ALS). These mutations are spread all over the protein. It is well docume...

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Bibliographic Details
Main Authors: Lucia Banci, Ivano Bertini, Mirela Boca, Stefania Girotto, Manuele Martinelli, Joan Selverstone Valentine, Miguela Vieru
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2250751?pdf=render

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