A Standardized Extract of Petasites hybridus L., Containing the Active Ingredients Petasins, Acts as a Pro-Oxidant and Triggers Apoptosis through Elevating of NF-κB in a Highly Invasive Human Breast Cancer Cell Line

A Standardized Extract of Petasites hybridus L., Containing the Active Ingredients Petasins, Acts as a Pro-Oxidant and Triggers Apoptosis through Elevating of NF-κB in a Highly Invasive Human Breast Cancer Cell Line

Background: Common butterbur (Petasites hybridus L.) is a traditional medicinal plant with numerous therapeutic properties among which is its recently uncovered anti-tumor activity. The present study aims to examine the activity of a standardized Bulgarian Petasites hybridus L. root extract, contain...

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Bibliographic Details
Main Authors: Sonia Apostolova, Tsvetelina Oreshkova, Veselina Uzunova, Irina Georgieva, Liliana Maslenkova, Rumiana Tzoneva
Format: Article
Language:English
Published: IMR Press 2023-06-01
Series:Frontiers in Bioscience-Landmark
Subjects:
petasites hybridus l.
petasins
apoptosis
oxidative stress
nf-κb
anticancer effects
Online Access:https://www.imrpress.com/journal/FBL/28/6/10.31083/j.fbl2806111

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