Mitochondrial Genetics Reinforces Multiple Layers of Interaction in Alzheimer’s Disease

Mitochondrial Genetics Reinforces Multiple Layers of Interaction in Alzheimer’s Disease

Nuclear DNA has been the main source of genome-wide loci association in neurodegenerative diseases, only partially accounting for the heritability of Alzheimer’s Disease (AD). In this context, mitochondrial DNA (mtDNA) is gaining more attention. Here, we investigated mitochondrial genes and genetic...

Full description

Bibliographic Details
Main Authors: Giovanna Chaves Cavalcante, Leonardo Miranda Brito, Ana Paula Schaan, Ândrea Ribeiro-dos-Santos, Gilderlanio Santana de Araújo, on behalf of Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomedicines
Subjects:
differential expression
epistasis
mtDNA
Alzheimer’s Disease
cerebrospinal fluid
TAU
Online Access:https://www.mdpi.com/2227-9059/10/4/880

Similar Items

Similar Items