| Summary: | The studies on the selective synthesis of dialkyl selenide compounds <b>1</b> were presented. Overcoming the complexity and difficulty of selenides (R-Se-R) and/or multiselenides (R-Se<sub>n</sub>-R; <i>n</i> ≥ 2), we aimed to optimize the reaction condition for the tolerable preparation of sodium selenide (Na<sub>2</sub>Se) by reducing Se with NaBH<sub>4</sub>, and then to achieve selective syntheses of dialkyl selenides <b>1</b> by subsequently treating the obtained sodium selenide with alkyl halides (RX). Consequently, various dialkyl selenides <b>1</b> were efficiently synthesized in good-to-moderate yields. The investigations on reaction pathways and solvent studies were also described.
|
|---|