Nonadherent culture method promotes MSC-mediated vascularization in myocardial infarction via miR-519d/VEGFA pathway

Nonadherent culture method promotes MSC-mediated vascularization in myocardial infarction via miR-519d/VEGFA pathway

Abstract Background Mesenchymal stem cells (MSCs) can provide therapeutic benefits for myocardial infarction (MI) recovery; however, the molecular mechanism by which MSCs improve the heart function is unclear. Methods Microarray analysis was performed to examine the expression profiling of human MSC...

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Bibliographic Details
Main Authors: Baoping Deng, Xianlan Zhang, Yi Liang, Haiming Jiang, Weizhao Huang, Yinmeng Wu, Weiping Deng
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Myocardial infarction
VEGFA
Angiogenesis
miR-519d
Nonadherent culture
Online Access:http://link.springer.com/article/10.1186/s13287-020-01780-x

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