Colorimetric and Label-Free Optical Detection of Pb<sup>2+</sup> Ions via Colloidal Gold Nanoparticles
The detection of the lead heavy metal (Pb) in water is crucial in many chemical processes, as it is associated with serious health hazards. Here, we report the selective and precise colorimetric detection of Pb<sup>2+</sup> ions in water, exploiting the aggregation and self-assembly mech...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/13/8/819 |
| _version_ | 1797585345518239744 |
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| author | Jasmin A. Flowers Monique J. Farrell Gugu Rutherford Aswini K. Pradhan |
| author_facet | Jasmin A. Flowers Monique J. Farrell Gugu Rutherford Aswini K. Pradhan |
| author_sort | Jasmin A. Flowers |
| collection | DOAJ |
| description | The detection of the lead heavy metal (Pb) in water is crucial in many chemical processes, as it is associated with serious health hazards. Here, we report the selective and precise colorimetric detection of Pb<sup>2+</sup> ions in water, exploiting the aggregation and self-assembly mechanisms of glutathione (GSH)-functionalized gold nanoparticles (GNPs). The carboxyl functional groups are able to create coordination complexes with Pb<sup>2+</sup>, inducing aggregation amongst the GSH-GNPs in the presence of Pb<sup>2+</sup> due to the chelation of the GSH ligands. The resulting aggregation amongst the GSH-GNPs in the presence of Pb<sup>2+</sup> increases the aggregate size depending on the available Pb<sup>2+</sup> ions, affecting the plasmonic coupling. This causes a substantial shift in the plasmon wavelength to a longer wavelength side with increasing Pb<sup>2+</sup> concentration, resulting in a red-to-blue colorimetric or visual change, enabling the instant determination of lead content in water. |
| first_indexed | 2024-03-11T00:05:46Z |
| format | Article |
| id | doaj.art-cc8068a10927491488ae3ace2dd501f0 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-11T00:05:46Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-cc8068a10927491488ae3ace2dd501f02023-11-19T00:25:42ZengMDPI AGBiosensors2079-63742023-08-0113881910.3390/bios13080819Colorimetric and Label-Free Optical Detection of Pb<sup>2+</sup> Ions via Colloidal Gold NanoparticlesJasmin A. Flowers0Monique J. Farrell1Gugu Rutherford2Aswini K. Pradhan3Boston Scientific, Maple Grove, MN 55311, USAFTL at Northrop Grumman, Washington, DC 20088, USANASA Langley Research Center, Langley Boulevard, Hampton, VA 23681, USADepartment of Physics, Hampton University, Hampton, VA 23668, USAThe detection of the lead heavy metal (Pb) in water is crucial in many chemical processes, as it is associated with serious health hazards. Here, we report the selective and precise colorimetric detection of Pb<sup>2+</sup> ions in water, exploiting the aggregation and self-assembly mechanisms of glutathione (GSH)-functionalized gold nanoparticles (GNPs). The carboxyl functional groups are able to create coordination complexes with Pb<sup>2+</sup>, inducing aggregation amongst the GSH-GNPs in the presence of Pb<sup>2+</sup> due to the chelation of the GSH ligands. The resulting aggregation amongst the GSH-GNPs in the presence of Pb<sup>2+</sup> increases the aggregate size depending on the available Pb<sup>2+</sup> ions, affecting the plasmonic coupling. This causes a substantial shift in the plasmon wavelength to a longer wavelength side with increasing Pb<sup>2+</sup> concentration, resulting in a red-to-blue colorimetric or visual change, enabling the instant determination of lead content in water.https://www.mdpi.com/2079-6374/13/8/819gold nanoparticlessurface plasmonscalorimetric detection of metal ions |
| spellingShingle | Jasmin A. Flowers Monique J. Farrell Gugu Rutherford Aswini K. Pradhan Colorimetric and Label-Free Optical Detection of Pb<sup>2+</sup> Ions via Colloidal Gold Nanoparticles Biosensors gold nanoparticles surface plasmons calorimetric detection of metal ions |
| title | Colorimetric and Label-Free Optical Detection of Pb<sup>2+</sup> Ions via Colloidal Gold Nanoparticles |
| title_full | Colorimetric and Label-Free Optical Detection of Pb<sup>2+</sup> Ions via Colloidal Gold Nanoparticles |
| title_fullStr | Colorimetric and Label-Free Optical Detection of Pb<sup>2+</sup> Ions via Colloidal Gold Nanoparticles |
| title_full_unstemmed | Colorimetric and Label-Free Optical Detection of Pb<sup>2+</sup> Ions via Colloidal Gold Nanoparticles |
| title_short | Colorimetric and Label-Free Optical Detection of Pb<sup>2+</sup> Ions via Colloidal Gold Nanoparticles |
| title_sort | colorimetric and label free optical detection of pb sup 2 sup ions via colloidal gold nanoparticles |
| topic | gold nanoparticles surface plasmons calorimetric detection of metal ions |
| url | https://www.mdpi.com/2079-6374/13/8/819 |
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