In Vitro Anthelmintic Areca catechu Crude Aqueous Extract Against Haemonchus contortus in The Sheep
Haemonchosis is a gastrointestinal parasitic disease in sheep caused by Haemonchus contortus. The biggest economic losses due to this disease are mortality, decreased production, stunted growth, and low body weight. The existence of resistance to synthetic anthelmintics causes the development of res...
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| Format: | Article |
| Language: | Indonesian |
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Universitas Gadjah Mada
2022-08-01
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| Series: | Jurnal Sain Veteriner |
| Subjects: | |
| Online Access: | https://journal.ugm.ac.id/jsv/article/view/70399 |
| _version_ | 1827941005543866368 |
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| author | Annisa Putri Cahyani Budi Purwo Widiarso Supriyanto - Wida Wahidah Mubarokah |
| author_facet | Annisa Putri Cahyani Budi Purwo Widiarso Supriyanto - Wida Wahidah Mubarokah |
| author_sort | Annisa Putri Cahyani |
| collection | DOAJ |
| description | Haemonchosis is a gastrointestinal parasitic disease in sheep caused by Haemonchus contortus. The biggest economic losses due to this disease are mortality, decreased production, stunted growth, and low body weight. The existence of resistance to synthetic anthelmintics causes the development of research on alternative treatments to herbal anthelmintics to be a strategic step. This study aims to analyze the effect of Areca catechu on Haemonchus contortus in vitro so that the Lethal Concentration 50 (LC 50) can be determined. This study was divided into 9 groups. Group I was treated with 2.5% A. catechu crude aqueous extract; group II was treated with 5% of A. catechu crude aqueous extract; group III was treated with 7.5% A. catechu crude aqueous extract; group IV was treated with 10% of A. catechu crude aqueous extract; group V was treated with 12.5% A. catechu crude aqueous extract; group VI was treated with 15% A. catechu crude aqueous extract; Group VII was treated with 17.5% A. catechu crude aqueous extract, group VIII was a negative control (0.9% NaCl) and group IX was a positive control (Albendazole). The mortality of H. contortus was recorded every hour until the worm mortality was 100%. The results were then analyzed using the Reed and Muench method. Based on the in vitro test of Areca catechu crude aqueous extract against H.contortus it can cause mortality in worms with an Lethal Concentration 50 (LC 50) calculation result of 11.11%. |
| first_indexed | 2024-03-13T09:30:35Z |
| format | Article |
| id | doaj.art-cc848528ed694c1385c67ea62caa55b0 |
| institution | Directory Open Access Journal |
| issn | 2407-3733 |
| language | Indonesian |
| last_indexed | 2024-03-13T09:30:35Z |
| publishDate | 2022-08-01 |
| publisher | Universitas Gadjah Mada |
| record_format | Article |
| series | Jurnal Sain Veteriner |
| spelling | doaj.art-cc848528ed694c1385c67ea62caa55b02023-05-26T02:51:45ZindUniversitas Gadjah MadaJurnal Sain Veteriner2407-37332022-08-0140218318710.22146/jsv.7039932352In Vitro Anthelmintic Areca catechu Crude Aqueous Extract Against Haemonchus contortus in The SheepAnnisa Putri Cahyani0Budi Purwo Widiarso1Supriyanto -2Wida Wahidah Mubarokah3Politeknik Pembangunan Pertanian Yogyakarta MagelangPoliteknik Pembangunan Pertanian Yogyakarta MagelangPoliteknik Pembangunan Pertanian Yogyakarta MagelangPoliteknik Pembangunan Pertanian Yogyakarta MagelangHaemonchosis is a gastrointestinal parasitic disease in sheep caused by Haemonchus contortus. The biggest economic losses due to this disease are mortality, decreased production, stunted growth, and low body weight. The existence of resistance to synthetic anthelmintics causes the development of research on alternative treatments to herbal anthelmintics to be a strategic step. This study aims to analyze the effect of Areca catechu on Haemonchus contortus in vitro so that the Lethal Concentration 50 (LC 50) can be determined. This study was divided into 9 groups. Group I was treated with 2.5% A. catechu crude aqueous extract; group II was treated with 5% of A. catechu crude aqueous extract; group III was treated with 7.5% A. catechu crude aqueous extract; group IV was treated with 10% of A. catechu crude aqueous extract; group V was treated with 12.5% A. catechu crude aqueous extract; group VI was treated with 15% A. catechu crude aqueous extract; Group VII was treated with 17.5% A. catechu crude aqueous extract, group VIII was a negative control (0.9% NaCl) and group IX was a positive control (Albendazole). The mortality of H. contortus was recorded every hour until the worm mortality was 100%. The results were then analyzed using the Reed and Muench method. Based on the in vitro test of Areca catechu crude aqueous extract against H.contortus it can cause mortality in worms with an Lethal Concentration 50 (LC 50) calculation result of 11.11%.https://journal.ugm.ac.id/jsv/article/view/70399anthelminticareca cathecuhaemonchus contortusin vitrolc50 |
| spellingShingle | Annisa Putri Cahyani Budi Purwo Widiarso Supriyanto - Wida Wahidah Mubarokah In Vitro Anthelmintic Areca catechu Crude Aqueous Extract Against Haemonchus contortus in The Sheep Jurnal Sain Veteriner anthelmintic areca cathecu haemonchus contortus in vitro lc50 |
| title | In Vitro Anthelmintic Areca catechu Crude Aqueous Extract Against Haemonchus contortus in The Sheep |
| title_full | In Vitro Anthelmintic Areca catechu Crude Aqueous Extract Against Haemonchus contortus in The Sheep |
| title_fullStr | In Vitro Anthelmintic Areca catechu Crude Aqueous Extract Against Haemonchus contortus in The Sheep |
| title_full_unstemmed | In Vitro Anthelmintic Areca catechu Crude Aqueous Extract Against Haemonchus contortus in The Sheep |
| title_short | In Vitro Anthelmintic Areca catechu Crude Aqueous Extract Against Haemonchus contortus in The Sheep |
| title_sort | in vitro anthelmintic areca catechu crude aqueous extract against haemonchus contortus in the sheep |
| topic | anthelmintic areca cathecu haemonchus contortus in vitro lc50 |
| url | https://journal.ugm.ac.id/jsv/article/view/70399 |
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