Vitamin D and gastrointestinal diseases: inflammatory bowel disease and colorectal cancer
Over the past 5 years, there has been a rapid resurgence of interest in vitamin D outside of its traditional role in metabolic bone disease. Some nontraditional roles ascribed to vitamin D include anti-inflammatory and immune-modulating effects. These effects have led to possible implications in the...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
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SAGE Publishing
2011-01-01
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Series: | Therapeutic Advances in Gastroenterology |
Online Access: | https://doi.org/10.1177/1756283X10377820 |
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author | Maitreyi Raman Andrew N. Milestone Julian R.F. Walters Ailsa L. Hart Subrata Ghosh |
author_facet | Maitreyi Raman Andrew N. Milestone Julian R.F. Walters Ailsa L. Hart Subrata Ghosh |
author_sort | Maitreyi Raman |
collection | DOAJ |
description | Over the past 5 years, there has been a rapid resurgence of interest in vitamin D outside of its traditional role in metabolic bone disease. Some nontraditional roles ascribed to vitamin D include anti-inflammatory and immune-modulating effects. These effects have led to possible implications in the pathophysiology of immune-mediated diseases including multiple sclerosis and inflammatory bowel disease (IBD). In addition, vitamin D insufficiency has been linked to higher rates of cancers including colon, prostate and breast cancers. Given these diverse associations of vitamin D and disease states, this review describes recent advances with regard to vitamin D and gastrointestinal diseases, in particular IBD and colorectal cancer. |
first_indexed | 2024-04-12T08:14:53Z |
format | Article |
id | doaj.art-cc855ef46a134816889809039dfc8172 |
institution | Directory Open Access Journal |
issn | 1756-283X 1756-2848 |
language | English |
last_indexed | 2024-04-12T08:14:53Z |
publishDate | 2011-01-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Therapeutic Advances in Gastroenterology |
spelling | doaj.art-cc855ef46a134816889809039dfc81722022-12-22T03:40:49ZengSAGE PublishingTherapeutic Advances in Gastroenterology1756-283X1756-28482011-01-01410.1177/1756283X10377820Vitamin D and gastrointestinal diseases: inflammatory bowel disease and colorectal cancerMaitreyi RamanAndrew N. MilestoneJulian R.F. WaltersAilsa L. HartSubrata GhoshOver the past 5 years, there has been a rapid resurgence of interest in vitamin D outside of its traditional role in metabolic bone disease. Some nontraditional roles ascribed to vitamin D include anti-inflammatory and immune-modulating effects. These effects have led to possible implications in the pathophysiology of immune-mediated diseases including multiple sclerosis and inflammatory bowel disease (IBD). In addition, vitamin D insufficiency has been linked to higher rates of cancers including colon, prostate and breast cancers. Given these diverse associations of vitamin D and disease states, this review describes recent advances with regard to vitamin D and gastrointestinal diseases, in particular IBD and colorectal cancer.https://doi.org/10.1177/1756283X10377820 |
spellingShingle | Maitreyi Raman Andrew N. Milestone Julian R.F. Walters Ailsa L. Hart Subrata Ghosh Vitamin D and gastrointestinal diseases: inflammatory bowel disease and colorectal cancer Therapeutic Advances in Gastroenterology |
title | Vitamin D and gastrointestinal diseases: inflammatory bowel disease and colorectal cancer |
title_full | Vitamin D and gastrointestinal diseases: inflammatory bowel disease and colorectal cancer |
title_fullStr | Vitamin D and gastrointestinal diseases: inflammatory bowel disease and colorectal cancer |
title_full_unstemmed | Vitamin D and gastrointestinal diseases: inflammatory bowel disease and colorectal cancer |
title_short | Vitamin D and gastrointestinal diseases: inflammatory bowel disease and colorectal cancer |
title_sort | vitamin d and gastrointestinal diseases inflammatory bowel disease and colorectal cancer |
url | https://doi.org/10.1177/1756283X10377820 |
work_keys_str_mv | AT maitreyiraman vitamindandgastrointestinaldiseasesinflammatoryboweldiseaseandcolorectalcancer AT andrewnmilestone vitamindandgastrointestinaldiseasesinflammatoryboweldiseaseandcolorectalcancer AT julianrfwalters vitamindandgastrointestinaldiseasesinflammatoryboweldiseaseandcolorectalcancer AT ailsalhart vitamindandgastrointestinaldiseasesinflammatoryboweldiseaseandcolorectalcancer AT subrataghosh vitamindandgastrointestinaldiseasesinflammatoryboweldiseaseandcolorectalcancer |