AVALIAÇÃO CLÍNICA DE BOVINOS INOCULADOS COM VENENO DE Crotalus durissus terrificus DETOXIFICADO POR IODAÇÃO E IODAÇÃO COM ENCAPSULAÇÃO EM LIPOSOMAS

The efficacy of detoxification of the crotalic venom for cattle by iodination and iodination plus encapsulation methods was clinically evaluated. Eleven 18-month-old heifers, weighing 160 kg in average, were used in this study. Groups of five animals were inoculated intramuscularly with 0.03mg/kg wi...

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Main Authors: Luiz Alberto Lago, Marilia Martins Melo, Luis Guilherme Diniz Heneine, Ernani Paulino Lago, Neide Judith Faria Oliveira, Paulo Gabriel Pereira Silva Junior
Format: Article
Language:English
Published: Universidade Federal de Goiás 2012-06-01
Series:Ciência Animal Brasileira
Subjects:
Online Access:http://www.revistas.ufg.br/index.php/vet/article/view/7653/11160
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author Luiz Alberto Lago
Marilia Martins Melo
Luis Guilherme Diniz Heneine
Ernani Paulino Lago
Neide Judith Faria Oliveira
Paulo Gabriel Pereira Silva Junior
author_facet Luiz Alberto Lago
Marilia Martins Melo
Luis Guilherme Diniz Heneine
Ernani Paulino Lago
Neide Judith Faria Oliveira
Paulo Gabriel Pereira Silva Junior
author_sort Luiz Alberto Lago
collection DOAJ
description The efficacy of detoxification of the crotalic venom for cattle by iodination and iodination plus encapsulation methods was clinically evaluated. Eleven 18-month-old heifers, weighing 160 kg in average, were used in this study. Groups of five animals were inoculated intramuscularly with 0.03mg/kg with either the detoxified non-encapsulated venom or the detoxified encapsulated venom. One control animal received the same dose of non-detoxified venom by the same route. Clinical evaluations were performed every two hours after venom inoculation (T0 - T 24). All clinical parameters (behaviour, posture, temperature, cardiac, respiratory and rumen movements frequencies, color of mucous membrane, sensorial and motor functions, and alterations at the inoculation site) were within the normal standards of the species throughout the studied period. It could be concluded that iodination of the crotalic venom, with or without incorporation into liposomes, suppresses the clinical manifestations of the crotalic envenomation in cattle.
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spelling doaj.art-cc9613b5595d40beb26716b82d9c47c62022-12-21T17:33:57ZengUniversidade Federal de GoiásCiência Animal Brasileira1518-27971089-68912012-06-01132234239AVALIAÇÃO CLÍNICA DE BOVINOS INOCULADOS COM VENENO DE Crotalus durissus terrificus DETOXIFICADO POR IODAÇÃO E IODAÇÃO COM ENCAPSULAÇÃO EM LIPOSOMASLuiz Alberto LagoMarilia Martins MeloLuis Guilherme Diniz HeneineErnani Paulino LagoNeide Judith Faria OliveiraPaulo Gabriel Pereira Silva JuniorThe efficacy of detoxification of the crotalic venom for cattle by iodination and iodination plus encapsulation methods was clinically evaluated. Eleven 18-month-old heifers, weighing 160 kg in average, were used in this study. Groups of five animals were inoculated intramuscularly with 0.03mg/kg with either the detoxified non-encapsulated venom or the detoxified encapsulated venom. One control animal received the same dose of non-detoxified venom by the same route. Clinical evaluations were performed every two hours after venom inoculation (T0 - T 24). All clinical parameters (behaviour, posture, temperature, cardiac, respiratory and rumen movements frequencies, color of mucous membrane, sensorial and motor functions, and alterations at the inoculation site) were within the normal standards of the species throughout the studied period. It could be concluded that iodination of the crotalic venom, with or without incorporation into liposomes, suppresses the clinical manifestations of the crotalic envenomation in cattle.http://www.revistas.ufg.br/index.php/vet/article/view/7653/11160bovineCrotalusvenom
spellingShingle Luiz Alberto Lago
Marilia Martins Melo
Luis Guilherme Diniz Heneine
Ernani Paulino Lago
Neide Judith Faria Oliveira
Paulo Gabriel Pereira Silva Junior
AVALIAÇÃO CLÍNICA DE BOVINOS INOCULADOS COM VENENO DE Crotalus durissus terrificus DETOXIFICADO POR IODAÇÃO E IODAÇÃO COM ENCAPSULAÇÃO EM LIPOSOMAS
Ciência Animal Brasileira
bovine
Crotalus
venom
title AVALIAÇÃO CLÍNICA DE BOVINOS INOCULADOS COM VENENO DE Crotalus durissus terrificus DETOXIFICADO POR IODAÇÃO E IODAÇÃO COM ENCAPSULAÇÃO EM LIPOSOMAS
title_full AVALIAÇÃO CLÍNICA DE BOVINOS INOCULADOS COM VENENO DE Crotalus durissus terrificus DETOXIFICADO POR IODAÇÃO E IODAÇÃO COM ENCAPSULAÇÃO EM LIPOSOMAS
title_fullStr AVALIAÇÃO CLÍNICA DE BOVINOS INOCULADOS COM VENENO DE Crotalus durissus terrificus DETOXIFICADO POR IODAÇÃO E IODAÇÃO COM ENCAPSULAÇÃO EM LIPOSOMAS
title_full_unstemmed AVALIAÇÃO CLÍNICA DE BOVINOS INOCULADOS COM VENENO DE Crotalus durissus terrificus DETOXIFICADO POR IODAÇÃO E IODAÇÃO COM ENCAPSULAÇÃO EM LIPOSOMAS
title_short AVALIAÇÃO CLÍNICA DE BOVINOS INOCULADOS COM VENENO DE Crotalus durissus terrificus DETOXIFICADO POR IODAÇÃO E IODAÇÃO COM ENCAPSULAÇÃO EM LIPOSOMAS
title_sort avaliacao clinica de bovinos inoculados com veneno de crotalus durissus terrificus detoxificado por iodacao e iodacao com encapsulacao em liposomas
topic bovine
Crotalus
venom
url http://www.revistas.ufg.br/index.php/vet/article/view/7653/11160
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