Cross-feeding between intestinal pathobionts promotes their overgrowth during undernutrition

Malnourished children experience a high burden of intestinal pathogens that exacerbate growth stunting, and preventing this pathogen overgrowth has proved challenging. Here the authors show that diet-specific bacterial crossfeeding contributes to the overgrowth of intestinal pathogens during child m...

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Main Authors: K. E. Huus, T. T. Hoang, A. Creus-Cuadros, M. Cirstea, S. L. Vogt, K. Knuff-Janzen, P. J. Sansonetti, P. Vonaesch, B. B. Finlay
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-27191-x
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author K. E. Huus
T. T. Hoang
A. Creus-Cuadros
M. Cirstea
S. L. Vogt
K. Knuff-Janzen
P. J. Sansonetti
P. Vonaesch
B. B. Finlay
author_facet K. E. Huus
T. T. Hoang
A. Creus-Cuadros
M. Cirstea
S. L. Vogt
K. Knuff-Janzen
P. J. Sansonetti
P. Vonaesch
B. B. Finlay
author_sort K. E. Huus
collection DOAJ
description Malnourished children experience a high burden of intestinal pathogens that exacerbate growth stunting, and preventing this pathogen overgrowth has proved challenging. Here the authors show that diet-specific bacterial crossfeeding contributes to the overgrowth of intestinal pathogens during child malnutrition.
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spelling doaj.art-cc9e757b1fd84013a1473c977361cfa62022-12-21T21:52:26ZengNature PortfolioNature Communications2041-17232021-11-0112111410.1038/s41467-021-27191-xCross-feeding between intestinal pathobionts promotes their overgrowth during undernutritionK. E. Huus0T. T. Hoang1A. Creus-Cuadros2M. Cirstea3S. L. Vogt4K. Knuff-Janzen5P. J. Sansonetti6P. Vonaesch7B. B. Finlay8Michael Smith Laboratories and Department of Microbiology and Immunology, University of British ColumbiaMichael Smith Laboratories and Department of Microbiology and Immunology, University of British ColumbiaMichael Smith Laboratories and Department of Microbiology and Immunology, University of British ColumbiaMichael Smith Laboratories and Department of Microbiology and Immunology, University of British ColumbiaMichael Smith Laboratories and Department of Microbiology and Immunology, University of British ColumbiaMichael Smith Laboratories and Department of Microbiology and Immunology, University of British ColumbiaUnité de Pathogénie Microbienne Moléculaire, Institut PasteurUnité de Pathogénie Microbienne Moléculaire, Institut PasteurMichael Smith Laboratories and Department of Microbiology and Immunology, University of British ColumbiaMalnourished children experience a high burden of intestinal pathogens that exacerbate growth stunting, and preventing this pathogen overgrowth has proved challenging. Here the authors show that diet-specific bacterial crossfeeding contributes to the overgrowth of intestinal pathogens during child malnutrition.https://doi.org/10.1038/s41467-021-27191-x
spellingShingle K. E. Huus
T. T. Hoang
A. Creus-Cuadros
M. Cirstea
S. L. Vogt
K. Knuff-Janzen
P. J. Sansonetti
P. Vonaesch
B. B. Finlay
Cross-feeding between intestinal pathobionts promotes their overgrowth during undernutrition
Nature Communications
title Cross-feeding between intestinal pathobionts promotes their overgrowth during undernutrition
title_full Cross-feeding between intestinal pathobionts promotes their overgrowth during undernutrition
title_fullStr Cross-feeding between intestinal pathobionts promotes their overgrowth during undernutrition
title_full_unstemmed Cross-feeding between intestinal pathobionts promotes their overgrowth during undernutrition
title_short Cross-feeding between intestinal pathobionts promotes their overgrowth during undernutrition
title_sort cross feeding between intestinal pathobionts promotes their overgrowth during undernutrition
url https://doi.org/10.1038/s41467-021-27191-x
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