ATM Dependent Silencing Links Nucleolar Chromatin Reorganization to DNA Damage Recognition
Resolution of DNA double-strand breaks (DSBs) is essential for the suppression of genome instability. DSB repair in transcriptionally active genomic regions represents a unique challenge that is associated with ataxia telangiectasia mutated (ATM) kinase-mediated transcriptional silencing. Despite em...
Main Authors: | Shane M. Harding, Jonathan A. Boiarsky, Roger A. Greenberg |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-10-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124715010104 |
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