Downregulation of circ-YES1 suppresses NSCLC migration and proliferation through the miR-142-3p–HMGB1 axis

Downregulation of circ-YES1 suppresses NSCLC migration and proliferation through the miR-142-3p–HMGB1 axis

Abstract Background Circular RNAs (circRNAs) are a new family of abundant regulatory RNAs with roles in various types of cancer. While the hsa_circ_0046701 (circ-YES1) function in non-small cell lung cancer (NSCLC) is unclear. Methods Circ-YES1 expression in normal pulmonary epithelial and NSCLC cel...

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Bibliographic Details
Main Authors: Mingming Jin, Yan Wang, Dawei Zhou, Wanchao Liu, Ruodong Han, Yongbin Chi
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Respiratory Research
Subjects:
Non-small cell lung cancer
Circ-YES1
miR-142-3p
High mobility group protein B1
Proliferation
Migration
Online Access:https://doi.org/10.1186/s12931-023-02378-6

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