A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
<p>Abstract</p> <p>Background</p> <p>G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligands interact and activate GPCRs, leading to signal transduction wit...
主要な著者: | , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
BMC
2005-04-01
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シリーズ: | BMC Bioinformatics |
オンライン・アクセス: | http://www.biomedcentral.com/1471-2105/6/104 |