A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models

<p>Abstract</p> <p>Background</p> <p>G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligands interact and activate GPCRs, leading to signal transduction wit...

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書誌詳細
主要な著者: Papasaikas Panagiotis K, Bagos Pantelis G, Sgourakis Nikolaos G, Hamodrakas Stavros J
フォーマット: 論文
言語:English
出版事項: BMC 2005-04-01
シリーズ:BMC Bioinformatics
オンライン・アクセス:http://www.biomedcentral.com/1471-2105/6/104