Zinc Finger Nucleases as tools to understand and treat human diseases
<p>Abstract</p> <p>Recent work has shown that it is possible to target regulatory elements to DNA sequences of an investigator's choosing, increasing the armamentarium for probing gene function. In this review, we discuss the development and use of designer zinc finger protein...
Main Authors: | Stokoe David, Davis David |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2010-07-01
|
Series: | BMC Medicine |
Online Access: | http://www.biomedcentral.com/1741-7015/8/42 |
Similar Items
-
Diversifying the structure of zinc finger nucleases for high-precision genome editing
by: David E. Paschon, et al.
Published: (2019-03-01) -
Design and Development of Artificial Zinc Finger Transcription Factors and Zinc Finger Nucleases to the hTERT Locus
by: Kimberly A Wilson, et al.
Published: (2013-01-01) -
Simultaneous screening and validation of effective zinc finger nucleases in yeast.
by: Ling Wang, et al.
Published: (2013-01-01) -
Knockout of Myostatin by Zinc-finger Nuclease in Sheep Fibroblasts and Embryos
by: Xuemei Zhang, et al.
Published: (2016-10-01) -
Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels.
by: Shondra M Pruett-Miller, et al.
Published: (2009-02-01)