Mood symptoms in cervical dystonia: Relationship with motor symptoms and quality of life
Background: Cervical dystonia (CD) has a high prevalence of anxiety and depression. The relationship between motor severity, mood symptoms and QoL is unclear and how to adequately assess these is also unknown. Instruments like the BAI, BDI and HADS are often used but items within these relating to s...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Clinical Parkinsonism & Related Disorders |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S259011252300004X |
| _version_ | 1797827802631766016 |
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| author | Shameer Rafee Mahmood Al-Hinai Gillian Douglas Ihedinachi Ndukwe Michael Hutchinson |
| author_facet | Shameer Rafee Mahmood Al-Hinai Gillian Douglas Ihedinachi Ndukwe Michael Hutchinson |
| author_sort | Shameer Rafee |
| collection | DOAJ |
| description | Background: Cervical dystonia (CD) has a high prevalence of anxiety and depression. The relationship between motor severity, mood symptoms and QoL is unclear and how to adequately assess these is also unknown. Instruments like the BAI, BDI and HADS are often used but items within these relating to somatic symptoms might influence the results. Methods: Patients with idiopathic cervical dystonia (CD) were included. The BAI, BDI, HADS, CIDP58 and TWSTRS2- severity score were used for assessment of motor, mood and QoL symptoms. Pearson’s correlations between motor and non-motor symptom scores were assessed. The psychometric properties of the psychiatric tools were measured and principal component analysis performed after identifying items that could correspond to somatic symptoms. Results: 201 participants were included. 42% of participants had either significant depression or anxiety symptoms or both when measured by BAI and BDI and 51% of patients met criteria on HADS. HADS-A and HADS-D, BAI and BDI were poorly correlated with TWSTRS2-S. The HADS-A and HADS-D both showed strong correlation with the sleep subdomain of CDIP58. Psychometric and principal component analysis on 149/201 participants did not reveal factor loadings consistent with the a priori somatic groupings. However mean scores were higher for somatic items. Conclusion: A good score on the CDIP58, a commonly used tool, does not indicate mild disease severity or minimal mood symptoms. Minimal motor symptoms, similarly, also does not imply a positive QoL. Clinicians should be mindful on ideal methods for performing a holistic assessment of CD patients. This likely warrants a combination of motor, QoL and mood assessment tools. |
| first_indexed | 2024-04-09T12:54:12Z |
| format | Article |
| id | doaj.art-ccb94131102e45c3a174fa9c05524fb3 |
| institution | Directory Open Access Journal |
| issn | 2590-1125 |
| language | English |
| last_indexed | 2024-04-09T12:54:12Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Parkinsonism & Related Disorders |
| spelling | doaj.art-ccb94131102e45c3a174fa9c05524fb32023-05-14T04:29:33ZengElsevierClinical Parkinsonism & Related Disorders2590-11252023-01-018100186Mood symptoms in cervical dystonia: Relationship with motor symptoms and quality of lifeShameer Rafee0Mahmood Al-Hinai1Gillian Douglas2Ihedinachi Ndukwe3Michael Hutchinson4Department of Neurology, St Vincent’s University Hospital, Merrion Road, Dublin, Ireland; School of Medicine, University College Dublin, Belfield, Dublin, Ireland; Corresponding author at: Department of Neurology, St Vincent’s University Hospital, Merrion Road, Dublin, Ireland.Department of Neurology, St Vincent’s University Hospital, Merrion Road, Dublin, IrelandDepartment of Neurology, St Vincent’s University Hospital, Merrion Road, Dublin, IrelandDepartment of Neurology, St Vincent’s University Hospital, Merrion Road, Dublin, IrelandDepartment of Neurology, St Vincent’s University Hospital, Merrion Road, Dublin, Ireland; School of Medicine, University College Dublin, Belfield, Dublin, IrelandBackground: Cervical dystonia (CD) has a high prevalence of anxiety and depression. The relationship between motor severity, mood symptoms and QoL is unclear and how to adequately assess these is also unknown. Instruments like the BAI, BDI and HADS are often used but items within these relating to somatic symptoms might influence the results. Methods: Patients with idiopathic cervical dystonia (CD) were included. The BAI, BDI, HADS, CIDP58 and TWSTRS2- severity score were used for assessment of motor, mood and QoL symptoms. Pearson’s correlations between motor and non-motor symptom scores were assessed. The psychometric properties of the psychiatric tools were measured and principal component analysis performed after identifying items that could correspond to somatic symptoms. Results: 201 participants were included. 42% of participants had either significant depression or anxiety symptoms or both when measured by BAI and BDI and 51% of patients met criteria on HADS. HADS-A and HADS-D, BAI and BDI were poorly correlated with TWSTRS2-S. The HADS-A and HADS-D both showed strong correlation with the sleep subdomain of CDIP58. Psychometric and principal component analysis on 149/201 participants did not reveal factor loadings consistent with the a priori somatic groupings. However mean scores were higher for somatic items. Conclusion: A good score on the CDIP58, a commonly used tool, does not indicate mild disease severity or minimal mood symptoms. Minimal motor symptoms, similarly, also does not imply a positive QoL. Clinicians should be mindful on ideal methods for performing a holistic assessment of CD patients. This likely warrants a combination of motor, QoL and mood assessment tools.http://www.sciencedirect.com/science/article/pii/S259011252300004XCervical dystoniaMood disorderRating scalesMotor severityQuality of life |
| spellingShingle | Shameer Rafee Mahmood Al-Hinai Gillian Douglas Ihedinachi Ndukwe Michael Hutchinson Mood symptoms in cervical dystonia: Relationship with motor symptoms and quality of life Clinical Parkinsonism & Related Disorders Cervical dystonia Mood disorder Rating scales Motor severity Quality of life |
| title | Mood symptoms in cervical dystonia: Relationship with motor symptoms and quality of life |
| title_full | Mood symptoms in cervical dystonia: Relationship with motor symptoms and quality of life |
| title_fullStr | Mood symptoms in cervical dystonia: Relationship with motor symptoms and quality of life |
| title_full_unstemmed | Mood symptoms in cervical dystonia: Relationship with motor symptoms and quality of life |
| title_short | Mood symptoms in cervical dystonia: Relationship with motor symptoms and quality of life |
| title_sort | mood symptoms in cervical dystonia relationship with motor symptoms and quality of life |
| topic | Cervical dystonia Mood disorder Rating scales Motor severity Quality of life |
| url | http://www.sciencedirect.com/science/article/pii/S259011252300004X |
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