Cystometric analysis of the transplanted bladder
ABSTRACT Objective Cystometric evaluation of the bladder after autotransplant and isogeneic transplant in female rats. Material and Methods Two groups were constituted: (A) bladder autotransplant with two subgroups: R1 – (control) and R2 – (bladder transplant); (B) isogeneic bladder transplant w...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Urologia
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| Series: | International Brazilian Journal of Urology |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382017000100112&lng=en&tlng=en |
| _version_ | 1818176753529520128 |
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| author | Jeová Nina Rocha |
| author_facet | Jeová Nina Rocha |
| author_sort | Jeová Nina Rocha |
| collection | DOAJ |
| description | ABSTRACT Objective Cystometric evaluation of the bladder after autotransplant and isogeneic transplant in female rats. Material and Methods Two groups were constituted: (A) bladder autotransplant with two subgroups: R1 – (control) and R2 – (bladder transplant); (B) isogeneic bladder transplant with three subgroups; T1 – (control); T2–T3, two subgroups observed for 30 and 60 days after transplant, respectively. All animals underwent cystometric evaluation. Afterwards, the bladders were removed for histological study. Results The transplanted bladders did not show significant changes in filling/storage and emptying/micturition functions after 30 and 60 days of evolution. Upon macroscopical evaluation, there was good revascularization and the tissue was well preserved. Cystometry results: Did not show significant differences in the micturition pressure in subgroups T2-T3, but did between subgroups R1−R2, T1−T2, and T1−T3. Significant differences were verified in the micturition interval between T1−T3, T2−T3, but not between R1−R2, T1−T2. There was significant difference in the micturition duration between T1−T3 but not between R1−R2, T1−T2 and T2−T3. No fistula was noted on the suture site nor leakage of urine in the abdominal cavity or signs of necrosis or retraction were observed. Conclusions Transplant of the bladder was shown to be a viable procedure. The results indicate that there was structural and functional regeneration of transplanted bladders, and these results indicate that it is possible that vascular endothelium growth and neurogenesis factors are involved and activated in the process of the preservation or survival of the transplanted organ. |
| first_indexed | 2024-12-11T20:21:12Z |
| format | Article |
| id | doaj.art-ccba42334f0041fbb3dce84009765806 |
| institution | Directory Open Access Journal |
| issn | 1677-6119 |
| language | English |
| last_indexed | 2024-12-11T20:21:12Z |
| publisher | Sociedade Brasileira de Urologia |
| record_format | Article |
| series | International Brazilian Journal of Urology |
| spelling | doaj.art-ccba42334f0041fbb3dce840097658062022-12-22T00:52:04ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-611943111212010.1590/s1677-5538.ibju.2015.0117S1677-55382017000100112Cystometric analysis of the transplanted bladderJeová Nina RochaABSTRACT Objective Cystometric evaluation of the bladder after autotransplant and isogeneic transplant in female rats. Material and Methods Two groups were constituted: (A) bladder autotransplant with two subgroups: R1 – (control) and R2 – (bladder transplant); (B) isogeneic bladder transplant with three subgroups; T1 – (control); T2–T3, two subgroups observed for 30 and 60 days after transplant, respectively. All animals underwent cystometric evaluation. Afterwards, the bladders were removed for histological study. Results The transplanted bladders did not show significant changes in filling/storage and emptying/micturition functions after 30 and 60 days of evolution. Upon macroscopical evaluation, there was good revascularization and the tissue was well preserved. Cystometry results: Did not show significant differences in the micturition pressure in subgroups T2-T3, but did between subgroups R1−R2, T1−T2, and T1−T3. Significant differences were verified in the micturition interval between T1−T3, T2−T3, but not between R1−R2, T1−T2. There was significant difference in the micturition duration between T1−T3 but not between R1−R2, T1−T2 and T2−T3. No fistula was noted on the suture site nor leakage of urine in the abdominal cavity or signs of necrosis or retraction were observed. Conclusions Transplant of the bladder was shown to be a viable procedure. The results indicate that there was structural and functional regeneration of transplanted bladders, and these results indicate that it is possible that vascular endothelium growth and neurogenesis factors are involved and activated in the process of the preservation or survival of the transplanted organ.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382017000100112&lng=en&tlng=enTransplantationUrinary BladderPatients |
| spellingShingle | Jeová Nina Rocha Cystometric analysis of the transplanted bladder International Brazilian Journal of Urology Transplantation Urinary Bladder Patients |
| title | Cystometric analysis of the transplanted bladder |
| title_full | Cystometric analysis of the transplanted bladder |
| title_fullStr | Cystometric analysis of the transplanted bladder |
| title_full_unstemmed | Cystometric analysis of the transplanted bladder |
| title_short | Cystometric analysis of the transplanted bladder |
| title_sort | cystometric analysis of the transplanted bladder |
| topic | Transplantation Urinary Bladder Patients |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382017000100112&lng=en&tlng=en |
| work_keys_str_mv | AT jeovaninarocha cystometricanalysisofthetransplantedbladder |