Downregulation of Interferon-β and Inhibition of TLR3 Expression are associated with Fatal Outcome of Severe Fever with Thrombocytopenia Syndrome

Downregulation of Interferon-β and Inhibition of TLR3 Expression are associated with Fatal Outcome of Severe Fever with Thrombocytopenia Syndrome

Abstract Severe Fever with Thrombocytopenia Syndrome (SFTS) is an emerging infectious disease with high mortality and increasing prevalence in the East Asia. Though the etiological agent has been identified as a novel Bunyavirus, cellular mechanisms of viral pathogenesis and host immune response to...

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Détails bibliographiques
Auteurs principaux: Peixin Song, Nan Zheng, Li Zhang, Yong Liu, Taoyu Chen, Changjun Bao, Zhifeng Li, Wei Yong, Yongyang Zhang, Chao Wu, Zhiwei Wu
Format: Article
Langue:English
Publié: Nature Portfolio 2017-07-01
Collection:Scientific Reports
Accès en ligne:https://doi.org/10.1038/s41598-017-06921-6

Internet

https://doi.org/10.1038/s41598-017-06921-6

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