Antidermatophytic Activity of the Fruticose Lichen Usnea orientalis
In the present study, the new biological sources in the form of lichen Usnea orientalis Motyka was screened for its antidermatophytic potential. Six species of dermatophytes were chosen on the basis of their prevalence for antidermatophytic assays, and the Clinical Laboratory Standard Institute (CLS...
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| Format: | Article |
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MDPI AG
2016-09-01
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| Series: | Medicines |
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| Online Access: | http://www.mdpi.com/2305-6320/3/3/24 |
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| author | Ashutosh Pathak Dalip Kumar Upreti Anupam Dikshit |
| author_facet | Ashutosh Pathak Dalip Kumar Upreti Anupam Dikshit |
| author_sort | Ashutosh Pathak |
| collection | DOAJ |
| description | In the present study, the new biological sources in the form of lichen Usnea orientalis Motyka was screened for its antidermatophytic potential. Six species of dermatophytes were chosen on the basis of their prevalence for antidermatophytic assays, and the Clinical Laboratory Standard Institute (CLSI)-recommended broth microdilution procedure was used to detect the efficacy of extract against dermatophytes. Thin layer chromatography of lichen extracts reveals the presence of two secondary metabolites viz. salazinic acid and usnic acid. U. orientalis extract exhibited promising antidermatophytic activity against all tested pathogens. Amongst all tested pathogens, Epidermophyton floccosum exhibited most susceptibility towards extract, whereas Trichophyton mentagrophytes exhibited the least susceptibility. Topical application of U. orientalis extract might be helpful in the cure of dermal infections. |
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| format | Article |
| id | doaj.art-ccbc320cef4e43eda4f127f43cde0a06 |
| institution | Directory Open Access Journal |
| issn | 2305-6320 |
| language | English |
| last_indexed | 2024-04-12T19:54:51Z |
| publishDate | 2016-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicines |
| spelling | doaj.art-ccbc320cef4e43eda4f127f43cde0a062022-12-22T03:18:43ZengMDPI AGMedicines2305-63202016-09-01332410.3390/medicines3030024medicines3030024Antidermatophytic Activity of the Fruticose Lichen Usnea orientalisAshutosh Pathak0Dalip Kumar Upreti1Anupam Dikshit2Biological Product Lab, Department of Botany, University of Allahabad, Allahabad 211002, IndiaLichenology Laboratory, CSIR-National Botanical Research Institute, Rana Pratap Marg, Lucknow 226001, IndiaBiological Product Lab, Department of Botany, University of Allahabad, Allahabad 211002, IndiaIn the present study, the new biological sources in the form of lichen Usnea orientalis Motyka was screened for its antidermatophytic potential. Six species of dermatophytes were chosen on the basis of their prevalence for antidermatophytic assays, and the Clinical Laboratory Standard Institute (CLSI)-recommended broth microdilution procedure was used to detect the efficacy of extract against dermatophytes. Thin layer chromatography of lichen extracts reveals the presence of two secondary metabolites viz. salazinic acid and usnic acid. U. orientalis extract exhibited promising antidermatophytic activity against all tested pathogens. Amongst all tested pathogens, Epidermophyton floccosum exhibited most susceptibility towards extract, whereas Trichophyton mentagrophytes exhibited the least susceptibility. Topical application of U. orientalis extract might be helpful in the cure of dermal infections.http://www.mdpi.com/2305-6320/3/3/24antidermatophyticdermatophytesDPPHLichen |
| spellingShingle | Ashutosh Pathak Dalip Kumar Upreti Anupam Dikshit Antidermatophytic Activity of the Fruticose Lichen Usnea orientalis Medicines antidermatophytic dermatophytes DPPH Lichen |
| title | Antidermatophytic Activity of the Fruticose Lichen Usnea orientalis |
| title_full | Antidermatophytic Activity of the Fruticose Lichen Usnea orientalis |
| title_fullStr | Antidermatophytic Activity of the Fruticose Lichen Usnea orientalis |
| title_full_unstemmed | Antidermatophytic Activity of the Fruticose Lichen Usnea orientalis |
| title_short | Antidermatophytic Activity of the Fruticose Lichen Usnea orientalis |
| title_sort | antidermatophytic activity of the fruticose lichen usnea orientalis |
| topic | antidermatophytic dermatophytes DPPH Lichen |
| url | http://www.mdpi.com/2305-6320/3/3/24 |
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